Recommendations for research

The guideline committee has made the following key recommendations for research.

1 Early warning scores in different settings

How accurate are early warning scores such as NEWS2 and CRB65, when applied to remote assessments of people with a suspected ARI via:

  • 111 and 999 call centres?

  • primary care?

How can the scores help to make clinical decisions about care pathways, for example, sending people home, to ARI virtual wards, or to same day emergency care?

For a short explanation of why the committee made this recommendation for research, see the rationale section on remote contact with NHS services at first presentation.

Full details of the evidence and the committee's discussion are in evidence summary D: acute respiratory infection.

How accurate are early warning scores such as NEWS2 and CRB65, when applied to face-to-face assessments of people with a suspected ARI in:

  • primary care, community pharmacy and other non-hospital, low-prevalence settings?

  • ARI hubs?

How can the scores help to make clinical decisions about care pathways, for example, sending people home, to ARI virtual wards, or to same day emergency care?

For a short explanation of why the committee made this recommendation for research, see the rationale section on in-person contact with NHS services at first presentation.

Full details of the evidence and the committee's discussion are in evidence summary D: acute respiratory infection.

2 Point-of-care microbiological tests

What is the role of point-of-care microbiological testing for guiding management in people with symptoms and signs of an ARI, taking into account good antimicrobial stewardship, cost, and clinical and cost effectiveness of the tests, and time taken to do the test and get a result?

For a short explanation of why the committee made this recommendation for research, see the rationale section on in-person contact with NHS services at first presentation.

Full details of the evidence and the committee's discussion are in evidence summary D: acute respiratory infection.

3 Costing antimicrobial stewardship

How can we quantify the impact on antimicrobial resistance of interventions that safely reduce antibiotic prescribing, in terms of future healthcare costs and health-related quality of life?

For a short explanation of why the committee made this recommendation for research, see the rationale section on in-person contact with NHS services at first presentation.

Full details of the evidence and the committee's discussion are in evidence summary D: acute respiratory infection.

  • National Institute for Health and Care Excellence (NICE)