Cetuximab for the treatment of locally advanced squamous cell cancer of the head and neck

  • Technology appraisal guidance
  • TA145
  • Published: 
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6 Recommendations for further research

6.1 A clinical trial on radiation therapy and cisplatin with or without cetuximab in patients with stage III or stage IV head and neck cancer (RTOG-0522) is currently recruiting patients.

6.2 The Committee recommends further research on the following:

  • Cetuximab in combination with radiotherapy compared with radiotherapy alone in patients with low Karnofsky performance-status scores.

  • Cetuximab in combination with radiotherapy compared with chemoradiotherapy in patients with high Karnofsky performance-status scores.

  • National Institute for Health and Care Excellence (NICE)