Ertugliflozin (Steglatro, Merck Sharp & Dohme) is indicated 'in adults aged 18 years and older with type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycaemic control:
as monotherapy in patients for whom the use of metformin is considered inappropriate due to intolerance or contraindications
in addition to other medicinal products for the treatment of diabetes'.
'The recommended starting dose of ertugliflozin is 5 mg once daily. In patients tolerating ertugliflozin 5 mg once daily, the dose can be increased to 15 mg once daily if additional glycaemic control is needed.'
The list price of ertogluflozin is 5 mg (28 tablets) or 15 mg (28 tablets): £29.40 per pack (excluding VAT; company submission). Costs may vary in different settings because of negotiated procurement discounts.