NICE is unable to make a recommendation about the use in the NHS of vericiguat for treating chronic heart failure with reduced ejection fraction. This is because Bayer did not provide an evidence submission for the appraisal and will not be launching the technology in the UK.


If NHS organisations wish to consider vericiguat for this indication, they should follow the advice on rational local decision making in the NHS Constitution for England and the NHS Commissioning Board and Clinical Commissioning Groups (Responsibilities and Standing Rules) Regulations 2012. This outlines the approach that should be taken when there is no NICE guidance.

NICE will review the position if the company decides that it wants to make an evidence submission.

ISBN: 978-1-4731-4272-5

  • National Institute for Health and Care Excellence (NICE)