Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process:
STA Standard
ID number:
11905

Provisional Schedule

Expected publication:
10 June 2026

Project Team

Project lead
Jeremy Powell

Email enquiries

If you have any queries please email TACommB@nice.org.uk


External Assessment Group:
Centre for Reviews and Dissemination and Centre for Health Economics, University of York

Stakeholders

Companies sponsors
Madrigal Pharmaceuticals (resmetirom)
Others
Department of Health and Social Care
 
NHS England
Patient carer groups
British Liver Trust
Professional groups
British Association for the Study of the Liver (BASL)
 
British Hepatology Pharmacy Group
 
Royal College of Physicians
 
UK Clinical Pharmacy Association
Associated public health groups
Public Health Wales
 
UK Health Security Agency
Comparator companies
Alliance Pharmaceuticals (vitamin E) - confidentiality agreement not signed, not participating
 
Brown & Burk UK (pioglitazone) - confidentiality agreement not signed, not participating
 
Kora Healthcare (vitamin E) - confidentiality agreement not signed, not participating
 
Mylan (pioglitazone) - confidentiality agreement not signed, not participating
 
Neon Healthcare (pioglitazone) - confidentiality agreement not signed, not participating
 
Novo Nordisk Ltd (semaglutide)
 
Sandoz (pioglitazone) - confidentiality agreement not signed, not participating
General commentators
All Wales Therapeutics and Toxicology Centre
 
British National Formulary
 
Department of Health - Northern Ireland
 
Healthcare Improvement Scotland
 
Medicines and Healthcare products Regulatory Agency
 
Scottish Medicines Consortium
 
Welsh Government

Timeline

Key events during the development of the guidance:

Date Update
14 May 2026 Committee meeting: 1
29 December 2025 A Technical Engagement consultation took place with registered stakeholders. The Committee meeting was delayed to allow more time for this appraisal. - Note added to the project documents
12 December 2025 Note - Note added to the project documents
10 July 2025 Invitation to participate
10 July 2025 In progress. Final scope published.
16 April 2025 Referral
11 April 2025 Note added to the project documents
13 September 2023 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual