3 Other information

3.1 Scope and how this guideline was developed

NICE guidelines are developed in accordance with a scope that defines what the guideline will and will not cover.

The scope for this guideline included initial management; evaluation of the accuracy of clinical features in leading to a diagnosis; evaluation of the accuracy and interpretation of biomarkers and ultrasound in diagnosis; pharmacological interventions to prevent miscarriage; evaluation of the effectiveness of early pregnancy assessment units; evaluation of different management strategies for both miscarriage and ectopic pregnancy; emotional and psychological support for women with pain and bleeding in early pregnancy, and those who experience early pregnancy loss; and the provision of anti-D rhesus prophylaxis for women with miscarriage or ectopic pregnancy.

The guideline does not cover the emergency management of acute presentations of shock and collapse; management of other problems in the first trimester unrelated to pain and bleeding caused by miscarriage or ectopic pregnancy; ongoing management of the pregnancy after the first trimester (that is, 13 completed weeks or more); and additional treatment and care needed by women with recurrent miscarriage.

How this guideline was developed

NICE commissioned the National Collaborating Centre for Women's and Children's Health to develop this guideline. The Centre established a Guideline Development Group (see section 4), which reviewed the evidence and developed the recommendations.

The methods and processes for developing NICE clinical guidelines are described in The guidelines manual.

3.2 Related NICE guidance

Details are correct at the time of publication (Dec 2012). Further information is available on the NICE website.



Under development

NICE is developing the following guidance (details available from the NICE website):

  • Fertility (update). NICE clinical guideline. Publication date to be confirmed.

  • Diabetes in pregnancy (update). NICE clinical guideline. Publication date to be confirmed.

  • National Institute for Health and Care Excellence (NICE)