This guideline makes recommendations for the identification, treatment and management of anorexia nervosa, bulimia nervosa and atypical eating disorders (including binge eating disorder) in primary, secondary and tertiary care. The guideline applies to adults, adolescents and children aged 8 years and older.
126.96.36.199 Assessment of people with eating disorders should be comprehensive and include physical, psychological and social needs, and a comprehensive assessment of risk to self.
188.8.131.52 The level of risk to the patient's mental and physical health should be monitored as treatment progresses because it may increase – for example, following weight change or at times of transition between services in cases of anorexia nervosa.
184.108.40.206 For people with eating disorders presenting in primary care, GPs should take responsibility for the initial assessment and the initial coordination of care. This includes the determination of the need for emergency medical or psychiatric assessment.
220.127.116.11 Where management is shared between primary and secondary care, there should be clear agreement among individual healthcare professionals on the responsibility for monitoring patients with eating disorders. This agreement should be in writing (where appropriate using the care programme approach) and should be shared with the patient and, where appropriate, his or her family and carers.
18.104.22.168 Patients and, where appropriate, carers should be provided with education and information on the nature, course and treatment of eating disorders.
22.214.171.124 In addition to the provision of information, family and carers may be informed of self-help groups and support groups, and offered the opportunity to participate in such groups where they exist.
126.96.36.199 Healthcare professionals should acknowledge that many people with eating disorders are ambivalent about treatment. Healthcare professionals should also recognise the consequent demands and challenges this presents.
188.8.131.52 People with eating disorders should be assessed and receive treatment at the earliest opportunity.
184.108.40.206 Early treatment is particularly important for those with or at risk of severe emaciation and such patients should be prioritised for treatment.
220.127.116.11 Where laxative abuse is present, patients should be advised to gradually reduce laxative use and informed that laxative use does not significantly reduce calorie absorption.
18.104.22.168 Treatment of both subthreshold and clinical cases of an eating disorder in people with diabetes is essential because of the greatly increased physical risk in this group.
22.214.171.124 People with type 1 diabetes and an eating disorder should have intensive regular physical monitoring because they are at high risk of retinopathy and other complications.
126.96.36.199 Pregnant women with eating disorders require careful monitoring throughout the pregnancy and in the postpartum period.
188.8.131.52 Patients with an eating disorder who are vomiting should have regular dental reviews.
184.108.40.206 Patients with an eating disorder who are vomiting should be given appropriate advice on dental hygiene, which should include: avoiding brushing after vomiting; rinsing with a non-acid mouthwash after vomiting; and reducing an acid oral environment (for example, limiting acidic foods).
220.127.116.11 Healthcare professionals should advise people with eating disorders and osteoporosis or related bone disorders to refrain from physical activities that significantly increase the likelihood of falls.
18.104.22.168 Family members, including siblings, should normally be included in the treatment of children and adolescents with eating disorders. Interventions may include sharing of information, advice on behavioural management and facilitating communication.
22.214.171.124 In children and adolescents with eating disorders, growth and development should be closely monitored. Where development is delayed or growth is stunted despite adequate nutrition, paediatric advice should be sought.
126.96.36.199 Healthcare professionals assessing children and adolescents with eating disorders should be alert to indicators of abuse (emotional, physical and sexual) and should remain so throughout treatment.
188.8.131.52 The right to confidentiality of children and adolescents with eating disorders should be respected.
184.108.40.206 Healthcare professionals working with children and adolescents with eating disorders should familiarise themselves with national guidelines and their employers' policies in the area of confidentiality.
1.1.6 Identification and screening of eating disorders in primary care and non-mental health settings
220.127.116.11 Target groups for screening should include young women with low body mass index (BMI) compared with age norms, patients consulting with weight concerns who are not overweight, women with menstrual disturbances or amenorrhoea, patients with gastrointestinal symptoms, patients with physical signs of starvation or repeated vomiting, and children with poor growth.
18.104.22.168 When screening for eating disorders one or two simple questions should be considered for use with specific target groups (for example, "Do you think you have an eating problem?" and "Do you worry excessively about your weight?").
22.214.171.124 Young people with type 1 diabetes and poor treatment adherence should be screened and assessed for the presence of an eating disorder.
126.96.36.199 In anorexia nervosa, although weight and BMI are important indicators they should not be considered the sole indicators of physical risk (as they are unreliable in adults and especially in children).
188.8.131.52 In assessing whether a person has anorexia nervosa, attention should be paid to the overall clinical assessment (repeated over time), including rate of weight loss, growth rates in children, objective physical signs and appropriate laboratory tests.
184.108.40.206 Patients with enduring anorexia nervosa not under the care of a secondary care service should be offered an annual physical and mental health review by their GP.
The delivery of psychological interventions should be accompanied by regular monitoring of a patient's physical state including weight and specific indicators of increased physical risk.
Common elements of the psychological treatment of anorexia nervosa
220.127.116.11 Therapies to be considered for the psychological treatment of anorexia nervosa include cognitive analytic therapy (CAT), cognitive behaviour therapy (CBT), interpersonal psychotherapy (IPT), focal psychodynamic therapy and family interventions focused explicitly on eating disorders.
18.104.22.168 Patient and, where appropriate, carer preference should be taken into account in deciding which psychological treatment is to be offered.
22.214.171.124 The aims of psychological treatment should be to reduce risk, to encourage weight gain and healthy eating, to reduce other symptoms related to an eating disorder, and to facilitate psychological and physical recovery.
Outpatient psychological treatments in first episode and later episodes
126.96.36.199 Most people with anorexia nervosa should be managed on an outpatient basis, with psychological treatment (with physical monitoring) provided by a healthcare professional competent to give it and to assess the physical risk of people with eating disorders.
188.8.131.52 Outpatient psychological treatment for anorexia nervosa should normally be of at least 6 months' duration.
184.108.40.206 For patients with anorexia nervosa, if during outpatient psychological treatment there is significant deterioration, or the completion of an adequate course of outpatient psychological treatment does not lead to any significant improvement, more intensive forms of treatment (for example, a move from individual therapy to combined individual and family work; or day-care or inpatient care) should be considered.
220.127.116.11 Dietary counselling should not be provided as the sole treatment for anorexia nervosa.
Psychological aspects of inpatient care
18.104.22.168 For inpatients with anorexia nervosa, a structured symptom-focused treatment regimen with the expectation of weight gain should be provided in order to achieve weight restoration. It is important to carefully monitor the patient's physical status during refeeding.
22.214.171.124 Psychological treatment should be provided which has a focus both on eating behaviour and attitudes to weight and shape, and on wider psychosocial issues with the expectation of weight gain.
126.96.36.199 Rigid inpatient behaviour modification programmes should not be used in the management of anorexia nervosa.
Post-hospitalisation psychological treatment
188.8.131.52 Following inpatient weight restoration, people with anorexia nervosa should be offered outpatient psychological treatment that focuses both on eating behaviour and attitudes to weight and shape, and on wider psychosocial issues, with regular monitoring of both physical and psychological risk.
184.108.40.206 The length of outpatient psychological treatment and physical monitoring following inpatient weight restoration should typically be at least 12 months.
Additional considerations for children and adolescents with anorexia nervosa
220.127.116.11 Family interventions that directly address the eating disorder should be offered to children and adolescents with anorexia nervosa.
18.104.22.168 Children and adolescents with anorexia nervosa should be offered individual appointments with a healthcare professional separate from those with their family members or carers.
22.214.171.124 The therapeutic involvement of siblings and other family members should be considered in all cases because of the effects of anorexia nervosa on other family members.
126.96.36.199 In children and adolescents with anorexia nervosa, the need for inpatient treatment and the need for urgent weight restoration should be balanced alongside the educational and social needs of the young person.
There is a very limited evidence base for the pharmacological treatment of anorexia nervosa. A range of drugs may be used in the treatment of comorbid conditions but caution should be exercised in their use given the physical vulnerability of many people with anorexia nervosa.
188.8.131.52 Medication should not be used as the sole or primary treatment for anorexia nervosa.
184.108.40.206 Caution should be exercised in the use of medication for comorbid conditions such as depressive or obsessive– compulsive features as they may resolve with weight gain alone.
220.127.116.11 When medication is used to treat people with anorexia nervosa, the side effects of drug treatment (in particular, cardiac side effects) should be carefully considered and discussed with the patient because of the compromised cardiovascular function of many people with anorexia nervosa.
18.104.22.168 Healthcare professionals should be aware of the risk of drugs that prolong the QTc interval on the ECG; for example, antipsychotics, tricyclic antidepressants, macrolide antibiotics, and some antihistamines. In patients with anorexia nervosa at risk of cardiac complications, the prescription of drugs with side effects that may compromise cardiac functioning should be avoided.
22.214.171.124 If the prescription of medication that may compromise cardiac functioning is essential, ECG monitoring should be undertaken.
126.96.36.199 All patients with a diagnosis of anorexia nervosa should have an alert placed in their prescribing record concerning the risk of side effects.
Anorexia nervosa carries considerable risk of serious physical morbidity. Awareness of the risk, careful monitoring and, where appropriate, close liaison with an experienced physician are important in the management of the physical complications of anorexia nervosa.
Managing weight gain
188.8.131.52 In most patients with anorexia nervosa, an average weekly weight gain of
0.5–1 kg in inpatient settings and 0.5 kg in outpatient settings should be an aim of treatment. This requires about 3500 to 7000 extra calories a week.
184.108.40.206 Regular physical monitoring, and in some cases treatment with a multi-vitamin/multi-mineral supplement in oral form, is recommended for people with anorexia nervosa during both inpatient and outpatient weight restoration.
220.127.116.11 Total parenteral nutrition should not be used for people with anorexia nervosa, unless there is significant gastrointestinal dysfunction.
18.104.22.168 Healthcare professionals should monitor physical risk in patients with anorexia nervosa. If this leads to the identification of increased physical risk, the frequency of the monitoring and nature of the investigations should be adjusted accordingly.
22.214.171.124 People with anorexia nervosa and their carers should be informed if the risk to their physical health is high.
126.96.36.199 The involvement of a physician or paediatrician with expertise in the treatment of medically at-risk patients with anorexia nervosa should be considered for all individuals who are medically at-risk.
188.8.131.52 Pregnant women with either current or remitted anorexia nervosa should be considered for more intensive prenatal care to ensure adequate prenatal nutrition and fetal development.
184.108.40.206 Oestrogen administration should not be used to treat bone density problems in children and adolescents as this may lead to premature fusion of the epiphyses.
220.127.116.11 Whenever possible patients should be engaged and treated before reaching severe emaciation. This requires both early identification and intervention. Effective monitoring and engagement of patients at severely low weight, or with falling weight, should be a priority.
Feeding against the will of the patient
18.104.22.168 Feeding against the will of the patient should be an intervention of last resort in the care and management of anorexia nervosa.
22.214.171.124 Feeding against the will of the patient is a highly specialised procedure requiring expertise in the care and management of those with severe eating disorders and the physical complications associated with it. This should only be done in the context of the Mental Health Act 1983 or Children Act 1989.
126.96.36.199 When making the decision to feed against the will of the patient, the legal basis for any such action must be clear.
This section considers those aspects of the service system relevant to the treatment and management of anorexia nervosa.
188.8.131.52 Most people with anorexia nervosa should be treated on an outpatient basis.
184.108.40.206 Inpatient treatment or day patient treatment should be considered for people with anorexia nervosa whose disorder has not improved with appropriate outpatient treatment, or for whom there is a significant risk of suicide or severe self-harm.
220.127.116.11 Inpatient treatment should be considered for people with anorexia nervosa whose disorder is associated with high or moderate physical risk.
18.104.22.168 Where inpatient management is required for people with anorexia nervosa, this should be provided within reasonable travelling distance to enable the involvement of relatives and carers in treatment, to maintain social and occupational links and to avoid difficulty in transition between primary and secondary care services. This is particularly important in the treatment of children and adolescents.
22.214.171.124 People with anorexia nervosa requiring inpatient treatment should be admitted to a setting that can provide the skilled implementation of refeeding with careful physical monitoring (particularly in the first few days of refeeding), in combination with psychosocial interventions.
126.96.36.199 Healthcare professionals without specialist experience of eating disorders, or in situations of uncertainty, should consider seeking advice from an appropriate specialist when contemplating a compulsory admission for a patient with anorexia nervosa, regardless of the age of the patient.
188.8.131.52 Healthcare professionals managing patients with anorexia nervosa, especially those with the binge–purging sub-type, should be aware of the increased risk of self-harm and suicide, particularly at times of transition between services or service settings.
184.108.40.206 Healthcare professionals should ensure that children and adolescents with anorexia nervosa who have reached a healthy weight have the increased energy and necessary nutrients available in their diet to support further growth and development.
220.127.116.11 In the nutritional management of children and adolescents with anorexia nervosa, carers should be included in any dietary education or meal planning.
18.104.22.168 Admission of children and adolescents with anorexia nervosa should be to age-appropriate facilities (with the potential for separate children and adolescent services), which have the capacity to provide appropriate educational and related activities.
22.214.171.124 When a young person with anorexia nervosa refuses treatment that is deemed essential, consideration should be given to the use of the Mental Health Act 1983 or the right of those with parental responsibility to override the young person's refusal.
126.96.36.199 Relying indefinitely on parental consent to treatment should be avoided. It is recommended that the legal basis under which treatment is being carried out should be recorded in the patient's case notes, and this is particularly important in the case of children and adolescents.
188.8.131.52 For children and adolescents with anorexia nervosa, where issues of consent to treatment are highlighted, healthcare professionals should consider seeking a second opinion from an eating disorders specialist.
184.108.40.206 If the patient with anorexia nervosa and those with parental responsibility refuse treatment, and treatment is deemed to be essential, legal advice should be sought in order to consider proceedings under the Children Act 1989.
220.127.116.11 As a possible first step, patients with bulimia nervosa should be encouraged to follow an evidence-based self-help programme.
18.104.22.168 Healthcare professionals should consider providing direct encouragement and support to patients undertaking an evidence-based self-help programme as this may improve outcomes. This may be sufficient treatment for a limited subset of patients.
22.214.171.124 Cognitive behaviour therapy for bulimia nervosa (CBT-BN), a specifically adapted form of CBT, should be offered to adults with bulimia nervosa. The course of treatment should be for 16 to 20 sessions over 4 to 5 months.
126.96.36.199 When people with bulimia nervosa have not responded to or do not want CBT, other psychological treatments should be considered.
188.8.131.52 Interpersonal psychotherapy should be considered as an alternative to CBT, but patients should be informed it takes 8–12 months to achieve results comparable with cognitive behaviour therapy.
184.108.40.206 As an alternative or additional first step to using an evidence-based self-help programme, adults with bulimia nervosa may be offered a trial of an antidepressant drug.
220.127.116.11 Patients should be informed that antidepressant drugs can reduce the frequency of binge eating and purging, but the long-term effects are unknown. Any beneficial effects will be rapidly apparent.
18.104.22.168 Selective serotonin reuptake inhibitors (SSRIs) (specifically fluoxetine) are the drugs of first choice for the treatment of bulimia nervosa in terms of acceptability, tolerability and reduction of symptoms.
22.214.171.124 For people with bulimia nervosa, the effective dose of fluoxetine is higher than for depression (60 mg daily).
126.96.36.199 No drugs, other than antidepressants, are recommended for the treatment of bulimia nervosa.
Patients with bulimia nervosa can experience physical problems as a result of a range of behaviours associated with the condition. Awareness of the risks and careful monitoring should be a concern of all healthcare professionals working with people with this disorder.
188.8.131.52 Patients with bulimia nervosa who are vomiting frequently or taking large quantities of laxatives (especially if they are also underweight) should have their fluid and electrolyte balance assessed.
184.108.40.206 When electrolyte disturbance is detected, it is usually sufficient to focus on eliminating the behaviour responsible. In the small proportion of cases where supplementation is required to restore electrolyte balance, oral rather than intravenous administration is recommended, unless there are problems with gastrointestinal absorption.
The great majority of patients with bulimia nervosa can be treated as outpatients. There is a very limited role for the inpatient treatment of bulimia nervosa. This is primarily concerned with the management of suicide risk or severe self-harm.
220.127.116.11 The great majority of patients with bulimia nervosa should be treated in an outpatient setting.
18.104.22.168 For patients with bulimia nervosa who are at risk of suicide or severe self-harm, admission as an inpatient or day patient, or the provision of more intensive outpatient care, should be considered.
22.214.171.124 Psychiatric admission for people with bulimia nervosa should normally be undertaken in a setting with experience of managing this disorder.
126.96.36.199 Healthcare professionals should be aware that patients with bulimia nervosa who have poor impulse control, notably substance misuse, may be less likely to respond to a standard programme of treatment. As a consequence treatment should be adapted to the problems presented.
188.8.131.52 In the absence of evidence to guide the management of atypical eating disorders (also known as eating disorders not otherwise specified) other than binge eating disorder, it is recommended that the clinician considers following the guidance on the treatment of the eating problem that most closely resembles the individual patient's eating disorder.
184.108.40.206 As a possible first step, patients with binge eating disorder should be encouraged to follow an evidence-based self-help programme.
220.127.116.11 Healthcare professionals should consider providing direct encouragement and support to patients undertaking an evidence-based self-help programme as this may improve outcomes. This may be sufficient treatment for a limited subset of patients.
18.104.22.168 Cognitive behaviour therapy for binge eating disorder (CBT-BED), a specifically adapted form of CBT, should be offered to adults with binge eating disorder.
22.214.171.124 Other psychological treatments (interpersonal psychotherapy for binge eating disorder and modified dialectical behaviour therapy) may be offered to adults with persistent binge eating disorder.
126.96.36.199 Patients should be informed that all psychological treatments for binge eating disorder have a limited effect on body weight.
188.8.131.52 When providing psychological treatments for patients with binge eating disorder, consideration should be given to the provision of concurrent or consecutive interventions focusing on the management of any comorbid obesity.
184.108.40.206 Suitably adapted psychological treatments should be offered to adolescents with persistent binge eating disorder.
220.127.116.11 As an alternative or additional first step to using an evidence-based self-help programme, consideration should be given to offering a trial of an SSRI antidepressant drug to patients with binge eating disorder.
18.104.22.168 Patients with binge eating disorders should be informed that SSRIs can reduce binge eating, but the long-term effects are unknown. Antidepressant drug treatment may be sufficient treatment for a limited subset of patients.