2 The technologies
2.1 Three high‑sensitivity troponin assays were identified during scoping as being relevant to the assessment. All of the assays are CE‑marked and intended for use in a clinical laboratory setting. For the purposes of the assessment, a high‑sensitivity troponin assay was defined as an assay that has a coefficient of variation of 10% or less at the 99th percentile (the upper limit of the reference population), and which is able to detect cardiac troponin in at least 50% of the reference population. Additional details of the high‑sensitivity troponin assays included in the guidance are provided in section 4.