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Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment

  • Diagnostics guidance
  • Reference number: DG16
  • Published:  10 December 2014
  • Guidance
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  • Information for the public
  • Evidence
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  • Overview
  • 1 Recommendations
  • 2 The technology
  • 3 Clinical need and practice
  • 4 The diagnostic tests
  • 5 Outcomes
  • 6 Considerations
  • 7 Recommendations for further research
  • 8 Implementation
  • 9 Related NICE guidance
  • 10 Review
  • 11 Diagnostics Advisory Committee members and NICE project team
  • 12 Sources of evidence considered by the Committee
  • About this guidance

1 Recommendations

1.1 The My5‑FU assay is only recommended for use in research for guiding dose adjustment in people having fluorouracil chemotherapy by continuous infusion. The My5‑FU assay shows promise and the development of robust evidence is recommended to demonstrate its utility in clinical practice (see section 7).


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