2 The technologies

2 The technologies

2.1 The LISA‑TRACKER, IDKmonitor, and Promonitor enzyme‑linked immunosorbent assay (ELISA) kits are intended to be used for measuring the levels of tumour necrosis factor (TNF)‑alpha inhibitors and antibodies against TNF‑alpha inhibitors in the blood of people having TNF‑alpha‑inhibitor treatment for Crohn's disease. TNF‑alpha is a cell signalling protein that promotes inflammatory responses. Dysregulation of TNF‑alpha production can contribute to inflammatory diseases, such as Crohn's disease. TNF‑alpha inhibitors, such as infliximab and adalimumab, are given to people with Crohn's disease to inhibit TNF‑alpha production and suppress the inflammatory response.

  • National Institute for Health and Care Excellence (NICE)