6 Recommendations for further research

6 Recommendations for further research

6.1 The committee was aware that the ongoing Integrate study may address some of the uncertainties in this assessment relating to diagnosing and managing gastroenteritis in the community. It recommended further research to determine the clinical significance of discordant results between the new tests (the xTAG Gastrointestinal Pathogen Panel, the FilmArray GI Panel and the Faecal Pathogens B assay) and conventional tests. Studies should aim to collect clinical follow‑up data that may show which method correctly identifies clinically significant disease. The committee was particularly interested in further research to resolve the discordance between results that are positive with the new technologies and negative by conventional methods.

6.2 The committee recommended further research on resource use and clinical effects associated with using the xTAG Gastrointestinal Pathogen Panel, the FilmArray GI Panel and the Faecal Pathogens B assay. The committee was advised that outcomes and resource use may vary according to healthcare setting and case mix, and so research should take place in multicentre studies that take account of these factors. Outcome data that should be collected include but are not limited to:

  • length of stay in hospital

  • length of time in isolation

  • change of treatment plan as a result of testing.

  • National Institute for Health and Care Excellence (NICE)