The Department for Health and Social Care has asked NICE to carry out a Single Technology Appraisal of ixazomib with lenalidomide and dexamethasone for untreated multiple myeloma. For information, the company have advised that they will not be submitting a Marketing Authorisation Application to the European Medicines Agency for this indication in line with previously communicated timelines. Therefore, NICE has decided to suspend this appraisal from its current work programme. As this appraisal has been referred NICE will continue to monitor any development and will update interested parties if the situation changes.