The Department for Health and Social Care has asked NICE to conduct an appraisal of Novocart 3D for treating articular cartilage defects of the knee. For information, the company have informed NICE that they have withdrawn their EMA Marketing Authorisation Application for this indication at this time to wait for promising follow-up data. Therefore NICE has decided to suspend this appraisal from its current work programme. As this appraisal has been referred, NICE will continue to monitor any development and will update interested parties as and when the situation changes.