Asfotase alfa for treating paediatric-onset hypophosphatasia

Equality Impact Assessment (Guidance development) (PDF 233 KB)

Final evaluation determination

Final evaluation determination document (PDF 590 KB)

Committee papers (PDF 395 KB)

Public committee slides (PDF 255 KB)

Appeal

Alexion : Appeal letter (PDF 1.33 MB)

NICE : Scrutiny letter (MSWord 59 KB)

Alexion : Response to scrutiny letter (PDF 377 KB)

Alexion : Response to scrutiny letter (PDF 374 KB)

Alexion : Response to scrutiny letter (PDF 125 KB)

NICE : Final scrutiny letter (MSWord 57 KB)

Alexion : Written submission (PDF 297 KB)

British Pediatric and Adolescent Bone Group : Appeal letter (PDF 75 KB)

British Pediatric and Adolescent Bone Group : Scrutiny letter (MSWord 56 KB)

British Pediatric and Adolescent Bone Group : Final scrutiny letter (MSWord 55 KB)

Children Living with Inherited Metabolic Diseases : Appeal letter (PDF 166 KB)

NICE : Scrutiny letter (MSWord 57 KB)

Children Living with Inherited Metabolic Diseases : Response to scrutiny letter (MSWord 31 KB)

NICE : Final scrutiny letter (MSWord 55 KB)

Royal College of Pathologists : Appeal letter (MSWord 61 KB)

NICE : Scrutiny letter (MSWord 56 KB)

NICE : Final scrutiny letter (MSWord 54 KB)

Final evaluation determination

Final evaluation determination document (PDF 797 KB)

Committee papers (PDF 1.23 MB)

Evaluation consultation

Evaluation consultation document (PDF 548 KB)

Committee papers (PDF 1.22 MB)

Evaluation consultation

Evaluation consultation document (PDF 518 KB)

Committee papers (PDF 11.64 MB)

Hypophosphatasia - asfotase alfa (paediatric-onset) [ID758]: final scope (PDF 101 KB)

Hypophosphatasia - asfotase alfa (paediatric-onset) [ID758]: final matrix (PDF 99 KB)

Hypophosphatasia - asfotase alfa (paediatric-onset) [ID758]: NICE response to consultee and commentator comments on the draft scope and provisional matrix (PDF 283 KB)

Hypophosphatasia - asfotase alfa (paediatric-onset) [ID758]: equality impact assessment - scoping (PDF 63 KB)

Hypophosphatasia - asfotase alfa (paediatric-onset) [ID758]: draft scope (PDF 111 KB)

Hypophosphatasia - asfotase alfa (paediatric-onset) [ID758]: provisional matrix (PDF 98 KB)