Review decision - November 2025

2 Current guidance

Recommendations

2.1

CaRi‑Heart is not recommended for use in the NHS while further evidence is generated. It should only be used in research to predict cardiac risk in people with suspected coronary artery disease (CAD), while treatment strategies to reduce coronary inflammation and cardiac death are identified.

2.2

Further research is recommended on:

  • how clinical outcomes might change for people with suspected CAD who have had CaRi‑Heart testing and appropriate treatment

  • how CaRi‑Heart results affect clinical decision making compared with UK standard clinical practice

  • the costs to the NHS of using CaRi‑Heart

  • how well CaRi‑Heart predicts cardiac risk to validate it in a UK population; in particular, data should be generated in the following groups: women, people from different ethnic backgrounds, and people who do not have CAD identified on CT coronary angiography (CTCA).

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