The National Institute for Health and Care Excellence (NICE) issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on Reducing the risk of transmission of Creutzfeldt–Jakob disease (CJD) from surgical instruments used for interventional procedures on high-risk tissues in November 2006. NICE is currently updating this guidance. The new guidance will be published shortly. Until then the NHS should continue to follow the recommendations outlined in the current version of the guidance. The Interventional Procedures Advisory Committee (IPAC) will consider this procedure review and NICE will issue an interventional procedures consultation document about its safety and efficacy for 4 weeks’ public consultation. IPAC will then review the consultation document in the light of comments received and produce a final interventional procedures document, which will be considered by NICE before guidance is issued to the NHS in England, Wales, Scotland and Northern Ireland.
Status In progress
Process IP
ID number 1553
Description Creutzfeldt–Jakob disease (CJD) is caused by abnormal proteins (prions) that infect the brain. It is very rare and there is no cure. It causes brain damage and leads to death. Symptoms include depression, anxiety, delusions, hallucinations, tremors and loss of co-ordination. There is a chance that surgical instruments could spread CJD from 1 patient to another, even when they have been properly washed and disinfected. This is because prions are very difficult to remove or destroy. Special safety measures are needed for instruments that are used on tissues at high risk of containing prions.

Provisional Schedule

Expected publication 22 January 2020


Key events during the development of the guidance:

Date Update
19 June 2019 - 22 August 2019 Interventional procedure consultation

For further information on how we develop guidance, please see our page about NICE interventional procedures guidance