NICE has been notified about this procedure and it is part of its work programme. The Interventional Procedures Advisory Committee (IPAC) will consider this procedure and NICE will issue an interventional procedures consultation document about its safety and efficacy for 4 weeks’ public consultation. IPAC will then review the consultation document in the light of comments received and produce a final interventional procedures document, which will be considered by NICE before guidance is issued to the NHS in England, Wales, Scotland and Northern Ireland.
Status In progress
Process IP
ID number 1720
Description Fetoscopic prenatal repair is done before 26 weeks of pregnancy. It can be done using local, regional or general anaesthesia and with partial CO2 insufflation of the uterine cavity. Under ultrasound guidance the paediatric laparoscopy set (a fetoscope/endoscope) is introduced through a port followed by the introduction of additional ports to allow the passage of instruments. Once the fetus is positioned adequately, the skin around the fetal neural placode/elements is dissected. A biocellulose patch is placed between the neural elements (defect) and the skin. The skin is sutured using interrupted stitches over the patch or, for a large defect, a dermal regeneration patch substitute can be used for repair. A number of minor variations to the procedure have been described.

Provisional Schedule

Expected publication 29 January 2020


Key events during the development of the guidance:

Date Update
26 September 2019 - 24 October 2019 Interventional procedure consultation
14 May 2019 Provisional Committee Meeting dates (11 July 2019 and 10 October 2019)

For further information on how we develop guidance, please see our page about NICE interventional procedures guidance