NICE has been notified about this procedure and it is part of its work programme. The Interventional Procedures Advisory Committee (IPAC) will consider this procedure and NICE will issue an interventional procedures consultation document about its safety and efficacy for 4 weeks’ public consultation. IPAC will then review the consultation document in the light of comments received and produce a final interventional procedures document, which will be considered by NICE before guidance is issued to the NHS in England, Wales, Scotland and Northern Ireland.
Status In progress
Process IP
ID number 228
Description SIRT involves delivering microspheres containing radionuclides that emit beta radiation directly into the tumour via the hepatic artery. Under local anaesthesia with fluoroscopic guidance, the radioactive microspheres, which are made of glass, resin or poly(L-lactic acid), are injected into branches of the hepatic artery supplying the tumour. A percutaneous approach through the femoral or radial artery is used. The microspheres are designed to lodge in the small arteries within and surrounding the tumour and release high doses of radiation directly into the tumour. The procedure may be repeated depending on the response.

Provisional Schedule

Expected publication 26 February 2020


Key events during the development of the guidance:

Date Update
25 July 2019 - 22 August 2019 Interventional procedure consultation

For further information on how we develop guidance, please see our page about NICE interventional procedures guidance