NICE has been notified about this procedure and it is part of its work programme. The Interventional Procedures Advisory Committee (IPAC) will consider this procedure and NICE will issue an interventional procedures consultation document about its safety and efficacy for 4 weeks’ public consultation. IPAC will then review the consultation document in the light of comments received and produce a final interventional procedures document, which will be considered by NICE before guidance is issued to the NHS in England, Wales, Scotland and Northern Ireland.
Status In progress
Process IP
ID number 1148
Description Cyanoacrylate glue occlusion for varicose veins aims to close the veins by adherence then fibrosis of the lumen, without the need for tumescent anaesthesia and with reduced need for postoperative compression therapy. The procedure is done using local anaesthesia. An introducer sheath is inserted into the distal great saphenous vein and, using ultrasound guidance, a delivery catheter is advanced into position before the saphenofemoral junction. The proximal vein is compressed and medical glue is delivered in measured doses through the tip of the catheter to seal the vein. This is repeated at different positions as the catheter is withdrawn, using ultrasound imaging to monitor the procedure. The procedure may also be done in a similar way for the small saphenous vein.

Provisional Schedule

Expected publication 04 March 2020


Key events during the development of the guidance:

Date Update
24 October 2019 - 21 November 2019 Interventional procedure consultation

For further information on how we develop guidance, please see our page about NICE interventional procedures guidance