Overview

This guide describes the methods and processes, including expected timescales, that NICE follows when carrying out health technology evaluations. The methods and processes are designed to produce robust guidance for the NHS in an open, transparent and timely way, with appropriate contribution from stakeholders. Organisations invited to contribute to health technology evaluation development should read this manual in conjunction with the NICE-wide topic prioritisation: the manual.

Last reviewed: 31 March 2026

This manual has been updated to include the change to the cost-effectiveness threshold.