Status In progress
Process STA pre-2018
ID number 938

Provisional Schedule

Expected publication 12 June 2019

Project Team

Project lead Donna Barnes

Email enquiries

Evidence Review Group / Assessment Group Warwick Evidence, Warwick Medical School, University of Warwick


Companies sponsors Roche
Others Department of Health and Social Care
  NHS England
  Welsh Government
Patient carer groups Multiple Sclerosis Society
  Multiple Sclerosis Trust
Professional groups Association of British Neurologists
  Royal College of Physicians
  UK Clinical Pharmacy Association


Comparator companies None
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Welsh Health Specialised Services Committee
Relevant research groups None


Key events during the development of the guidance:

Date Update
09 May 2019 - 22 May 2019 Final appraisal document: 2
26 March 2019 Committee meeting: 3
30 October 2018 The final guidance for this appraisal will not be published on the website on 31st October 2018 as previously planned, as the appraisal has been paused while commercial discussions between the company and NHS England are taking place.
10 September 2018 - 21 September 2018 Final appraisal determination
02 August 2018 Committee meeting: 2
29 June 2018 - 19 July 2018 Appraisal consultation
06 June 2018 Committee meeting
16 November 2017 Following an update from the company on the regulatory process, this appraisal will be rescheduled to ensure the company can provide a submission relevant to the final indication wording. As a result, the discussion of this appraisal planned for Tuesday 06 March 2018 has been cancelled. The closing date for submissions will also be extended. Details of the updated timelines for this appraisal will be sent to stakeholders and published on the NICE website in due course.
02 October 2017 Invitation to participate
23 June 2017 Following on from advice received from the company this appraisal has been rescheduled. Therefore, we now anticipate that the appraisal will begin during late September 2017 when we will write to you about how you can get involved. The deadline for submissions is expected in approximately late November 2017.
25 January 2017 Draft scope documents
05 December 2016 Referral

For further information on how we develop guidance, please see our page about NICE technology appraisal guidance