Status In progress
Process STA
ID number 938

Provisional Schedule

Committee meeting 06 June 2018
Expected publication 31 October 2018

Project Team

Project lead Donna Barnes

Email enquiries


Companies sponsors Roche
Others Department of Health
  NHS Bromley CCG
  NHS England
  NHS North Lincolnshire CCG
  Welsh Government
Patient carer groups Brain and Spine Foundation
  Disability Rights UK
  Leonard Cheshire Disability
  Multiple Sclerosis National Therapy Centres
  Multiple Sclerosis Society
  Multiple Sclerosis Trust
  Multiple Sclerosis-UK
  Muslim Council of Britain
  Neurological Alliance
  South Asian Health Foundation
  Specialised Healthcare Alliance
  Sue Ryder
Professional groups Association of British Neurologists
  British Geriatrics Society
  British Neuropathological Society
  Institute of Neurology
  Primary Care Neurology Society
  Royal College of General Practitioners
  Royal College of Nursing
  Royal College of Pathologists
  Royal College of Physicians
  Royal Pharmaceutical Society
  Royal Society of Medicine
  Therapists in MS
  UK Clinical Pharmacy Association
  UK Multiple Sclerosis Specialist Nurse Association


Comparator companies None
General commentators and Toxicology Centre
  Allied Health Professionals Federation
  Board of Community Health Councils in Wales
  British National Formulary
  Care Quality Commission
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare Products Regulatory Agency
  Multiple Sclerosis Society Wales
  National Association of Primary Care
  National Pharmacy Association
  Neurological Alliance of Scotland
  NHS Alliance
  NHS Commercial Medicines Unit
  NHS Confederation
  Scottish Medicines Consortium
  Wales Neurological Alliance
  Welsh Health Specialised Services Committee
Relevant research groups Brain Research Trust
  British Neurological Research Trust
  Cochrane Multiple Sclerosis Group
  MRC Clinical Trials Unit
  National Hospital for Neurology and Neurosurgery
  National Institute for Health Research


Key events during the development of the guidance:

Date Update
16 November 2017 Following an update from the company on the regulatory process, this appraisal will be rescheduled to ensure the company can provide a submission relevant to the final indication wording. As a result, the discussion of this appraisal planned for Tuesday 06 March 2018 has been cancelled. The closing date for submissions will also be extended. Details of the updated timelines for this appraisal will be sent to stakeholders and published on the NICE website in due course.
02 October 2017 Invitation to participate
23 June 2017 Following on from advice received from the company this appraisal has been rescheduled. Therefore, we now anticipate that the appraisal will begin during late September 2017 when we will write to you about how you can get involved. The deadline for submissions is expected in approximately late November 2017.
25 January 2017 Draft scope documents
05 December 2016 Referral

For further information on how we develop guidance, please see our page about NICE technology appraisal guidance