Suggested remit - To appraise the clinical and cost effectiveness of durvalumab within its marketing authorisation for untreated metastatic non-small-cell lung cancer with no EGFR- or ALK-positive mutations
Referred 05/12/2017
 
Status Suspended
Process STA 2018
ID number 1331

Project Team

Project lead Kate Moore

Email enquiries

Timeline

Key events during the development of the guidance:

Date Update
17 October 2019 Suspended. Referred 05/12/2017
17 October 2019 The Department for Health and Social Care has asked NICE to carry out an appraisal of durvalumab for untreated metastatic non-small-cell lung cancer with no EGFR- or ALK-positive mutations. For information, the company have advised that they are no longer pursuing a Marketing Authorisation Application from the European Medicines Agency for this indication at this time. Therefore, NICE has decided to suspend this appraisal from its current work programme. As this appraisal has been referred NICE will continue to monitor any development and will update interested parties if the situation changes.
12 April 2019 As you will be aware, the Department for Health and Social Care has asked NICE to carry out a Single Technology Appraisal of durvalumab for untreated metastatic non-small-cell lung cancer with no EGFR- or ALK-positive mutations. However, following on from information received from the company regarding the recent results for the Phase III MYSTIC trial, the timelines for this appraisal are to be confirmed. As this appraisal has been referred, NICE will continue to monitor any developments and will provide an update as and when the situation changes.
28 September 2018 - 26 October 2018 Consultation on suggested remit, draft scope and provisional matrix of consultees and commentators
05 December 2017 In progress. Topic referred

For further information on how we develop guidance, please see our page about NICE technology appraisal guidance