Suggested remit: To appraise the clinical and cost effectiveness of pralsetinib within its marketing authorisation for treating RET fusion-positive advanced non-small-cell lung cancer.
 
Status In progress
Process STA 2018
ID number 3875

Provisional Schedule

Committee meeting 15 December 2021
Expected publication 09 March 2022

Project Team

Project lead Kate Moore

Email enquiries

Consultees

Companies sponsors Roche (pralsetinib)
Others Department of Health and Social care
  NHS Birmingham South and Central CCG
  NHS East Leicestershire and Rutland CCG
  NHS England
  Welsh Government
Patient carer groups Black Health Agency for Equality
  Cancer Black Care
  Cancer Equality
  Helen Rollason Cancer Charity
  Independent Cancer Patients Voice
  Macmillan Cancer Support
  Maggie’s Centres
  Marie Curie
  Roy Castle Lung Cancer Foundation
  South Asian Health Foundation
  Specialised Healthcare Alliance
  Tenovus Cancer Care
  UK Lung Cancer Coalition
Professional groups Association of Cancer Physicians
  Association of Respiratory Nurse Specialists
  British Geriatrics Society
  British Institute of Radiology
  British Psychosocial Oncology Society
  British Thoracic Oncology Group
  British Thoracic Society
  Cancer Research UK
  Lung Cancer Nursing UK
  National Heart and Lung Institute
  Primary Care Respiratory Society
  Royal College of General Practitioners
  Royal College of Nursing
  Royal College of Pathologists
  Royal College of Physicians
  Royal College of Radiologists
  Royal Pharmaceutical Society
  Royal Society of Medicine
  Society and College of Radiographers
  UK Clinical Pharmacy Association
  UK Oncology Nursing Society

Commentators

Associated public health groups Public Health England
  Public Health Wales
Comparator companies Accord Healthcare (cisplatin, carboplatin, docetaxel, gemcitabine, paclitaxel, vinorelbine)
  Actavis UK (gemcitabine, paclitaxel, pemetrexed, vinorelbine)
  Aspire Pharma (pemetrexed)
  Boehringer Ingelheim (nintedanib)
  Bristol-Myers Squibb Pharmaceuticals (ipilimumab, nivolumab)
  Celgene (paclitaxel, nab-paclitaxel)
  Consilient Health Ltd (carboplatin, vinorelbine)
  Dr Reddy’s Laboratories (docetaxel, pemetrexed)
  Eli Lilly (selpercatinib, pemetrexed)
  Fresenius Kabi (docetaxel, paclitaxel, pemetrexed)
  Fresenius Kabi Oncology (carboplatin, gemcitabine)
  Hospira UK (cisplatin, carboplatin, docetaxel, gemcitabine, paclitaxel)
  Medac GmbH (vinorelbine)
  Merck Sharp & Dohme (pembrolizumab)
  Organon Pharma (UK) (bevacizumab)
  Pfizer (bevacizumab, carboplatin, cisplatin, docetaxel, gemcitabine, paclitaxel)
  Pierre Fabre (vinorelbine)
  Roche (atezolizumab, bevacizumab)
  Sandoz (cisplatin)
  Sanofi (docetaxel)
  Seacross pharmaceuticals (docetaxel, paclitaxel, pemetrexed)
  Sun Pharma (carboplatin, gemcitabine)
  Teva UK (carboplatin, cisplatin, docetaxel, paclitaxel)
General commentators All Wales Therapeutic and Toxicology Centre
  Allied Health Professionals Federation
  Board of Community Health Councils in Wales
  British National Formulary
  Care Quality Commission
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare Products Regulatory Agency
  National Association of Primary Care
  National Pharmacy Association
  NHS Alliance
  NHS Confederation
  Scottish Medicines Consortium
  Welsh Health Specialised Services Committee
Relevant research groups Cochrane Lung Cancer Group
  Genomics England
  Institute of Cancer Research
  MRC Clinical Trials Unit
  National Cancer Research Institute
  National Cancer Research Network
  National Institute for Health Research

Timeline

Key events during the development of the guidance:

Date Update
26 April 2021 Invitation to participate
09 February 2021 - 09 March 2021 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
18 February 2021 In progress. DHSC referral received

For further information on how we develop guidance, please see our page about NICE technology appraisal guidance