Suggested remit: To appraise the clinical and cost effectiveness of lebrikizumab within its marketing authorisation for treating moderate to severe atopic dermatitis in people 12 years and over.
 
Status In progress
Technology type Medicine
Decision Selected
Reason for decision Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process STA Standard
ID number 4025

Project Team

Project lead Leena Issa

Email enquiries

External Assessment Group Southampton Health Technology Assessment Centre (SHTAC), University of Southampton

Stakeholders

Companies sponsors Almirall (lebrikizumab)
Others Department of Health and Social Care
  NHS England
Patient carer groups Eczema Outreach Support
  National Eczema Society
Professional groups British Association of Dermatologists
  Royal College of Physicians
Comparator companies AbbVie (upadacitinib) (confidentiality agreement signed, participating)
  Accord (azathioprine, methotrexate, mycophenolate mofetil) (confidentiality agreement not signed, not participating)
  Advanz Pharma (methotrexate) (confidentiality agreement not signed, not participating)
  Aspen (azathioprine) (confidentiality agreement not signed, not participating)
  Cipla (methotrexate) (confidentiality agreement not signed, not participating)
  Dexcel-Pharma Limited (ciclosporin) (confidentiality agreement not signed, not participating)
  Eli Lilly (baricitinib) (confidentiality agreement signed, participating)
  Ennogen (azathioprine) (confidentiality agreement not signed, not participating)
  Hospira (methotrexate) (confidentiality agreement not signed, not participating)
  Leo Pharma (tralokinumab) (confidentiality agreement not signed, not participating)
  Medac (methotrexate) (confidentiality agreement not signed, not participating)
  Morningside Healthcare (methotrexate) (confidentiality agreement not signed, not participating)
  Mylan (azathioprine, ciclosporin, mycophenolate mofetil) (confidentiality agreement not signed, not participating)
  Nordic Pharma (methotrexate) (confidentiality agreement not signed, not participating)
  Novartis Pharmaceuticals (ciclosporin, mycophenolate mofetil) (confidentiality agreement not signed, not participating)
  Orion Pharma (methotrexate) (confidentiality agreement not signed, not participating)
  Pfizer (abrocitinib, methotrexate) (confidentiality agreement not signed, not participating)
  Roche (mycophenolate mofetil) (confidentiality agreement not signed, not participating)
  Rosemont Pharmaceuticals (methotrexate) (confidentiality agreement not signed, not participating)
  Sandoz (methotrexate, mycophenolate mofetil) (confidentiality agreement not signed, not participating)
  Sanofi (dupilumab) (confidentiality agreement signed, participating)
  Strides Pharma (azathioprine) (confidentiality agreement not signed, not participating)
  Teva (mycophenolate mofetil) (confidentiality agreement not signed, not participating)
  Therakind (methotrexate) (confidentiality agreement not signed, not participating)
  Tilomed Laboratories (azathioprine, mycophenolate mofetil) (confidentiality agreement not signed, not participating)
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency
  Scottish Medicines Consortium
  Welsh Government
  Welsh Health Specialised Services Committee

Timeline

Key events during the development of the guidance:

Date Update
11 April 2024 Committee meeting
07 September 2023 Invitation to participate
23 May 2023 - 21 June 2023 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
23 May 2023 In progress. Scoping commenced
27 October 2021 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual