Suggested remit: To appraise the clinical and cost effectiveness of giredestrant with everolimus within its marketing authorisation for treating oestrogen-receptor positive HER2-negative advanced breast cancer after a cyclin-dependent kinase 4 and 6 inhibitor and endocrine treatment.

Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process:
STA Standard
ID number:
6576

Provisional Schedule

Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators: 6576:
17 November 2025 - 08 December 2025

Project Team

Project lead
Emily Richards

Email enquiries

If you have any queries please email scopingta@nice.org.uk

Timeline

Key events during the development of the guidance:

Date Update
17 November 2025 In progress. Scoping commencing
02 October 2025 To appraise the clinical and cost effectiveness of Everolimus + Giredestrant within its marketing authorisation for treating breast cancer
15 May 2025 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual