Lubiprostone for treating opioid induced constipation
 
Status Suspended
Process STA
Topic area
  • Digestive system

Provisional Schedule

Closing date for invited submissions / evidence submission: 28 January 2014
1st appraisal committee meeting: 07 May 2014

Project Team

Communications manager: TBC
Project manager:

Nicole Fisher

Technical Lead: TBC

Consultees

Manufacturers/sponsors Sucampo Pharma Europe (lubiprostone)
Others Department of Health
  Welsh Government
  NHS England
Patient/carer groups Bladder and Bowel Foundation
  Pain UK
  PromoCon
  IBS Network
Professional groups Association of Coloproctology of Great Britain and Ireland
  Association for Continence Advice
  Royal College of Nursing
  Royal College of Physicians

Commentators

Associated Guideline groups National Collaborating Centre for Cancer
Associated Public Health groups National Institute for Health and Care Excellence (NICE)
Comparator manufacturers Abbott Laboratories UK (lactulose) (Confidentiality agreement not signed, not participating)
  Actavis UK (glycerol suppositories), (Confidentiality agreement not signed, not participating)
  Amdipharm (methylcellulose)
  Bell Sons & Co (Druggists) Limited (arachis oil)
(Confidentiality agreement not signed, not participating)
  Bio-Health (psyllium husk) (Confidentiality agreement not signed, not participating)
  Boehringer Ingelheim UK (bisacodyl, docusate sodium, macrogol, sodium picosulphate) (Confidentiality agreement not signed, not participating)
  B R Pharmaceuticals (senna) (Confidentiality agreement not signed, not participating)
  Cardinal Health Martindale Products (glycerol suppositories, bisacodyl suppositories (Confidentiality agreement not signed, not participating)
  Casen Fleet Laboratories (sodium dihydrogen phosphate dihydrate/disodium hydrogen phosphate dodecahydrate enema)(Confidentiality agreement not signed, not participating)
  Chanelle Medical (bisacodyl, macrogol,)(Confidentiality agreement not signed, not participating)
  Dr. Reddy’s Laboratories UK (bisacodyl, macrogol)
(Confidentiality agreement not signed, not participating)
  Ecolab UK (arachis oil)(Confidentiality agreement not signed, not participating)
  Forest Laboratories UK (arachis oil enema, , phosphates enema) (Confidentiality agreement not signed, not participating)
  Hermal (ispaghula husk, glycerol suppositories, senna, Senokot direct relief suppositories)(Confidentiality agreement not signed, not participating)
  Intrapharm Laboratories (lactulose) (Confidentiality agreement not signed, not participating)
  J M Loveridge (arachis oil, methylcellulose)(Confidentiality agreement not signed, not participating)
  LPC Medical UK (ispaghula husk) (Confidentiality agreement not signed, not participating)
  Manx Healthcare (ispaghula husk) (Confidentiality agreement not signed, not participating)
  Meda Pharmaceuticals (macrogol) (Confidentiality agreement not signed, not participating)
  Napp Pharmaceuticals (dantron, naloxone-oxycodone)
  Norgine Pharmaceuticals (sterculia/frangula, macrogol, docusate sodium enema)
  Optima Consumer Health (arachis oil) (Confidentiality agreement not signed, not participating)
  Perrigo (bisacodyl suppositories, dantron, sodium citrate enema, senna) (Confidentiality agreement not signed, not participating)
  Pinewood Healthcare (sodium citrate enema, dantron)(Confidentiality agreement not signed, not participating)
  Potter’s Herbal Medicines UK (psyllium husk, senna)(Confidentiality agreement not signed, not participating)
  Shire Pharmaceuticals (prucalopride)
  Solvay Healthcare (lactulose) (Confidentiality agreement not signed, not participating)
  Teva UK (glycerol suppositories, lactulose, dantron, (Confidentiality agreement not signed, not participating)
  Thornton & Ross (macrogol, magnesium hydroxide, glycerol suppositories, senna) (Confidentiality agreement not signed, not participating)
  TMC Pharma (methylnaltrexone)
  UCB Pharma (sodium citrate enema, docusate sodium)(Confidentiality agreement not signed, not participating)
  Zentiva UK (dantron,) Confidentiality agreement not signed, not participating)
Evidence Review Group NHS Centre for Reviews and Dissemination & Centre for Health Economics – York
  National Institute for Health Research Health Technology Assessment Programme
General Commissioning Support Appraisals Service
  Department of Health,Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency

Timeline

Key events during the development of the guidance:

Date Update
04 April 2014 7 May 2014 -Committee meeting for this appraisal topic has been cancelled. The appraisal is suspended because the regulatory timeline has changed due to the MHRA not granting a license for this indication. The appraisal topic will be rescheduled into the NICE work programme when the regulatory next steps are known.’

For further information on how we develop guidance, please see our page about NICE technology appraisal guidance