The National Institute for Health and Care Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on percutaneous mitral valve leaflet repair for mitral regurgitation.


Mitral regurgitation occurs when the mitral valve does not close properly, allowing blood to leak backwards. This can lead to shortness of breath and the heart may be unable to pump enough blood to the rest of the body. During percutaneous mitral valve leaflet repair, a catheter is inserted through the skin via a large vein in the groin or neck and passed through to the heart. The two leaflets of the mitral valve are partially clipped or sewn together to reduce the amount of blood leaking backwards.

Coding and clinical classification codes for this guidance.

Is this guidance up to date?

We checked this guidance in December 2018 and we are updating it. See the guidance in development page for progress on the update.

Guidance development process

How we develop NICE interventional procedures guidance

Your responsibility

This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take this guidance fully into account, and specifically any special arrangements relating to the introduction of new interventional procedures. The guidance does not override the individual responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or guardian or carer. 

All problems (adverse events) related to a medicine or medical device used for treatment or in a procedure should be reported to the Medicines and Healthcare products Regulatory Agency using the Yellow Card Scheme.

Commissioners and/or providers have a responsibility to implement the guidance, in their local context, in light of their duties to have due regard to the need to eliminate unlawful discrimination, advance equality of opportunity, and foster good relations. Nothing in this guidance should be interpreted in a way that would be inconsistent with compliance with those duties. Providers should ensure that governance structures are in place to review, authorise and monitor the introduction of new devices and procedures.

Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible.

  • National Institute for Health and Care Excellence (NICE)