This document replaces previous guidance on percutaneous closure of patent foramen ovale for the prevention of cerebral embolic stroke (interventional procedure guidance 109).
1.1 Evidence on the safety of percutaneous closure of patent foramen ovale to prevent recurrent cerebral embolic events shows serious but infrequent complications. Evidence on its efficacy is adequate. Therefore this procedure may be used with normal arrangements for clinical governance, consent and audit.
1.2 The procedure should only be performed in units with appropriate arrangements for urgent cardiac surgical support in the event of complications.
1.3 Clinicians should enter details about all patients undergoing percutaneous closure of patent foramen ovale to prevent recurrent cerebral embolic events onto the UK Central Cardiac Audit Database.