2 Indications and current treatments
2.1 Depression is a common disorder, characterised by persistent sadness, loss of interest or pleasure, feelings of guilt, low self‑worth, tiredness, poor concentration, and disturbed sleep, appetite and libido. It is often accompanied by feelings of hopelessness and suicidal thoughts. Depression can last from weeks to years, and can be recurrent. It can substantially impair a person's ability to function at work or cope with daily life.
2.2 Treatments for depression include a range of psychological therapies, and antidepressant medications. In severe depression that has not responded to other treatments, electroconvulsive therapy is sometimes used.