Information for the public
In Dupuytren's disease, connective tissue in the palm of the hands thickens. This causes nodules (small, hard lumps) to form under the skin of the palm. Over time, the nodules can form cords of tissue. These cords can shorten and permanently bend the fingers towards the palm, reducing hand mobility and causing pain. Often, Dupuytren's disease is mild and doesn't need treatment. But treatment may help if the condition stops the hand working normally. It includes injections with a medication called collagenase, a needle to cut the contracted cords of tissue (needle fasciotomy) or, in severe cases, surgery.
NICE has looked at using radiation therapy as another treatment option.
NHS Choices may be a good place to find out more.