2 Indications and current treatments
2.1 Current treatment options for localised or locally advanced prostate cancer include 'watchful waiting', active surveillance, radiotherapy, radical prostatectomy, cryotherapy, high-intensity focused ultrasound, androgen deprivation therapy and chemotherapy (as recommended in NICE's guideline on prostate cancer: diagnosis and treatment).
2.2 Radiation therapy is an established curative treatment and can be either external-beam radiotherapy or brachytherapy (also called interstitial radiotherapy). Brachytherapy can be given at either low- or high-dose rates. Low-dose-rate brachytherapy may be used alone or in combination with external-beam radiotherapy.