3 Committee considerations

3 Committee considerations

The evidence

3.1 To inform the committee, NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 5 sources, which was discussed by the committee. The evidence included 1 randomised controlled trial and 4 case series, and is presented in table 2 of the interventional procedure overview. Other relevant literature is in the overview.

3.2 The specialist advisers and the committee considered the key efficacy outcomes to be: reduction in intraoperative pressure that persists long-term, reduction in glaucoma medications, and quality of life.

3.3 The specialist advisers and the committee considered the key safety outcomes to be: hypotony and loss of vision.

3.4 Patient commentary was sought but none was received.

Committee comments

3.5 The committee noted that the evidence they reviewed was based on a single device.

3.6 The committee noted that the procedure can be done with or without concomitant cataract surgery, but this guidance only covers the use of this procedure with phacoemulsification.

ISBN: 978-1-4731-2832-3

  • National Institute for Health and Care Excellence (NICE)