3.1 To inform the committee, NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 11 sources, which was discussed by the committee. The evidence included 1 retrospective comparative case series, 7 case series and 3 case reports, and is presented in table 2 of the interventional procedures overview. Other relevant literature is in the appendix of the overview.
3.2 The specialist advisers and the committee considered the key efficacy outcomes to be: reduction in intraocular pressure and reduction in glaucoma specific medication.
3.3 The specialist advisers and the committee considered the key safety outcomes to be: hypotony, loss of visual acuity and infection.
3.4 One commentary was received from a patient who had experience of this procedure, and was discussed by the committee.