3 Committee considerations
3.1 NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 6 sources, which was discussed by the committee. The evidence included 6 case series. It is presented in table 2 of the interventional procedures overview. Other relevant literature is in the appendix of the overview.
3.2 The professional experts and the committee considered the key efficacy outcomes to be: coronary artery patency, reduced cardiac-related symptoms, survival and improved quality of life.
3.3 The professional experts and the committee considered the key safety outcomes to be: major adverse cardiovascular events, coronary artery rupture or dissection, coronary thrombosis, distal embolisation and balloon rupture.
3.4 One patient organisation representing patients who have had this procedure provided submissions and these were discussed by the committee.