Recommendations for research

The guideline committee has made the following recommendations for research.

1 Immunotherapy after multimodality treatment

What is the effectiveness and cost effectiveness of immunotherapy in people with stage IIIA-N2 non-small-cell lung cancer following multimodality treatment including surgery?

To find out why the committee made the research recommendation on immunotherapy after multimodality treatment, see rationale and impact.

2 Stereotactic ablative radiotherapy compared with surgery

What is the effectiveness and cost effectiveness of stereotactic ablative radiotherapy (SABR) compared with surgery (for example, sublobar, wedge resection, lobectomy) for people with non-small-cell lung cancer (stage I and IIA) in whom surgery is suitable?

To find out why the committee made the research recommendation on SABR compared with surgery, see rationale and impact.

3 Routine contrast-enhanced brain CT

What is the effectiveness and cost effectiveness of routinely performing contrast-enhanced brain CT at the time of initial diagnosis and/or staging CT?

To find out why the committee made the research recommendation on routinely performing contrast-enhanced brain CT, see rationale and impact.

4 Prophylactic cranial irradiation compared with routine MRI follow-up in extensive-stage small-cell lung cancer

What is the effectiveness and cost effectiveness of prophylactic cranial irradiation compared with routine MRI follow-up in people with extensive-stage small-cell lung cancer without brain metastases?

To find out why the committee made the research recommendation on prophylactic cranial irradiation compared with routine MRI follow-up in extensive-stage small-cell lung cancer, see rationale and impact.

  • National Institute for Health and Care Excellence (NICE)