Thyroid disease: assessment and management

In October 2025, we reviewed the recommendations on managing primary hypothyroidism.

Surveillance decision

We will not update the recommendations. While it is likely that costs are now lower for liothyronine in the NHS, insufficient evidence of effectiveness was found to support updating current recommendations for the use of liothyronine for hypothyroidism. However, 3 ongoing trials were identified, and these will be added to our tracking system and assessed for impact once findings are published.