5 The Guideline Development Group, NICE project team, NICE quality assurance team and declarations of interest

5 The Guideline Development Group, NICE project team, NICE quality assurance team and declarations of interest

5.1 Guideline Development Group

Chris Cefai
Consultant in Clinical Microbiology and Infection Control, Betsi Cadwaladr University Health Board, North Wales

Esmita Charani (until 27 November 2014)
Academic Research Pharmacist, the National Centre for Infection Prevention and Management, Imperial College London and Honorary Clinical Pharmacist, Imperial College Healthcare NHS Trust

Lynne Craven
Lay member

Martin Duerden
Sessional/Locum GP, North Wales and Clinical Senior Lecturer, Centre for Health Economics and Medicines Evaluation, Bangor University

Heather Edmonds
Lead Medicines Optimisation and Antimicrobial Pharmacist, Leeds North Clinical Commissioning Group

Alastair Hay (Chair)
Professor of Primary Care and NIHR Research Professor, Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol; and GP, Concord Medical Centre, Bristol

Philip Howard
Consultant Antimicrobial Pharmacist, Leeds Teaching Hospitals NHS Trust

Sanjay Kalra
Consultant in Trauma and Orthopaedics and Clinical Lead for Infection Control, Royal Liverpool University Hospitals NHS Trust

Tessa Lewis (Vice Chair)
GP and Medical Adviser to All Wales Therapeutics and Toxicology Centre

Kym Lowder
Head of Medicines Management, Integrated Care 24 Limited, Kent

Cliodna McNulty
Head of Primary Care Unit, Public Health England

John Morris
Lay member

Sanjay Patel
Consultant in Paediatric Infectious Diseases and Immunology, University Hospital Southampton NHS Foundation Trust

Wendy Thompson
Associate Dentist, Sedbergh Dental Practice, Clinical Supervisor, Blackpool Teaching Hospitals NHS Foundation Trust, Lecturer in Antimicrobial Prescribing, Health Education NE

Susan Walsh
Lay member

5.2 NICE project team

Emma Aaron
Administrator, Medicines and Prescribing Centre, NICE

Anne‑Louise Clayton
Editor

Leighton Coombs
Data Analyst, Health Technology Intelligence, NICE (from July to December 2014)

Johanna Hulme
Project Lead and Associate Director, Medicines and Prescribing Centre, NICE

Debra Hunter
Assistant Project Manager, Medicines and Prescribing Centre, NICE (from 29 September 2014)

Dominick Moran
Data Analyst, Costing and Commissioning Implementation, NICE (from July to December 2014)

Greg Moran
Senior Adviser, Medicines and Prescribing Centre, NICE

Roberta Richey
Senior Adviser, Medicines and Prescribing Centre, NICE (from 1 August 2014)

Rebekah Robinson
Assistant Project Manager, Medicines and Prescribing Centre, NICE (until 26 September 2014)

Erin Whittingham
Public Involvement Adviser

5.3 NICE quality assurance team

Mark Baker
Clinical Adviser

Christine Carson
Guideline Lead

Louise Shires
Guideline Commissioning Manager

Judith Thornton
Technical Lead

5.4 Declarations of interests

The following members of the Guideline Development Group (GDG) made declarations of interests. All other GDG members stated that they had no interests to declare. The conflicts of interest policy (2007) was followed until September 2014, when an updated policy was published.

Member

Interest declared

Type of interest

Decision taken

Alastair Hay (Chair)

Member of Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection.

Personal specific non‑financial

Project lead will monitor for any potential conflict. Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc.

Would like to be aware of evidence gaps and GDG research recommendations that could influence future research programme.

Has an interest in the Longitude prize, no financial interests, no involvement in any new antimicrobials.

Alastair Hay (Chair)

No financial conflicts of interest to declare. Lead a group at the University of Bristol conducting research into primary care infections and antimicrobial resistance.

Personal non‑financial non‑specific

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc.

Esmita Charani

Published in peer reviewed journals.

Personal non‑financial non‑specific

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles. Reminded that opinions expressed that may be relevant to the guideline may lead to a conflict of interest.

Esmita Charani

Published author on research into antimicrobial stewardship interventions and behaviour change in this field including Cochrane reviews (one ongoing at present). Has also published research on use of mobile health technology to deliver antimicrobial stewardship interventions.

Personal non‑financial non‑specific

Chair and Project lead will monitor for any potential conflict. Also discussed with the NICE Medicines and Prescribing Centre Programme Director. Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles.

Salary is funded by the National Institute of Health Research on a grant investigating behaviour change in antimicrobial prescribing.

Non‑personal financial non‑specific

Honorary visiting researcher to Haukeland University in Norway where advice on the implementation of the national implementation of an antimicrobial stewardship programme.

Personal non‑financial non‑specific

Esmita Charani

Undertaking research at PhD level into antibiotic prescribing behaviours in secondary care.

Personal non‑financial non‑specific

Chair and Project lead will monitor for any potential conflict. Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles.

Published author in the field of antibiotic prescribing behaviours and antimicrobial stewardship.

Martin Duerden

Received personal payment (honoraria) plus reimbursement of expenses from Reckitt Benckiser (RB) to speak at 2 meetings in the last 12 months. The subject of the talks was antibiotic use in respiratory infections at each meeting but there was no promotion of products marketed by Reckitt Benckiser in the content.

Personal financial non‑specific

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles. Advised not to write for any publication until the guideline has published.

In the last 12 months has also received payment from the publishers of Pulse, GP and Prescriber for writing various articles on prescribing and therapeutics, including antibiotic use.

Personal financial non‑specific

Martin Duerden

Clinical Adviser on Prescribing for the Royal College of General Practitioners but does not receive payment for this.

Personal non‑specific non‑financial

None

Martin Duerden

Member of the Global Respiratory Infection Partnership (work declared above with Reckitt Benckiser done in this capacity). Now spoken at 4 meetings in the last 12 months.

Personal non‑specific non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles. Advised not to write for any publication until the guideline has published.

Member of the Paediatric Formulary Committee for the British National Formulary (BNF); payment not received for this.

Personal non‑specific non‑financial

On the editorial board of Prescriber (a Wiley publication) which is an unpaid position. Occasionally writes opinion‑based editorials and articles for this publication. Receives payments for these.

Personal non-specific non‑financial

In the last year was commissioned and co‑wrote a report on Polypharmacy for the King's Fund and received payment for this. Also spoke at a King's Fund seminar on the topic.

Personal non‑specific non‑financial

On the Editorial Board of Drug and Therapeutics Bulletin, a BMJ Group publication, this is a paid position.

Personal financial non‑specific

Has received small payments for articles on the Lipid Modification Clinical Guideline from Pulse and from Guidelines in Practice.

Personal financial non‑specific

Member of the NICE Guideline Development Group on lipid modification: cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease.

Personal non‑specific non‑financial

On the Medicines Committee for the Royal College of Paediatrics and Child Health – payment not received for this.

Personal non‑specific non‑financial

Member of the NICE technology appraisals Committee until October 2014. This is not a paid position.

Personal non‑specific non‑financial

Martin Duerden

Presented at workshops for commissioners introducing the proposed new national Antimicrobial Prescribing Quality Premium and guide commissioners towards resources and best practice – March 2015 in Leeds.

Personal non‑specific financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles. Chair and Project lead will monitor for any potential conflict.

Delivered a session on sharing success and the work that has been done in Leeds. No financial payment was received for presenting.

Personal non‑specific non‑financial

Heather Edmonds

Involved in a Royal College of Nursing published position statement which was sponsored by Pfizer.

Personal non‑specific non‑financial

None

Rose Gallagher

Paid consultancy work on antibiotics for the pharmaceutical industry: Pfizer (linezolid), Astellas (levofloxacin), AstraZeneca (ceftaroline), Novartis (daptomycin), Gilead (AmBisome).

Personal non‑specific non‑financial

Chair and Project lead will monitor for any potential conflict. Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc.

Philip Howard

Paid consultancy work with Danone on antimicrobial stewardship.

Non‑specific personal financial

Advised not to undertake any further consultancy work in this area during the development of the guideline through to publication.

Committee member of UK Clinical Pharmacy Association – Pharmacy Infection Network.

Council member of British Infection Association (until May 2013).

Council member of British Society of Antimicrobial Chemotherapy.

Represented International Pharmaceutical Federation (FIP) at WHO (World Health Organisation) Antimicrobial Resistance Strategic Technical Advisory Group (May 2014).

Published unpaid articles related to antimicrobial stewardship.

Spokesman on Antimicrobials for Royal Pharmaceutical Society.

Philip Howard

Involved in Antimicrobial Resistance Summit at the Royal Pharmaceutical Society in November 2014.

Personal non‑specific non‑financial

Advised not to undertake any further consultancy work in this area during the development of the guideline through to publication.

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc. Chair and Project lead will monitor for any potential conflict.

Philip Howard

Sponsorship to present work at international conferences (no money received directly):
European Association of Hospital Pharmacy (B. Braun 2013 and 2014)
– European Congress of Clinical Pharmacy and Infectious Diseases (Gilead 2014).
Received expenses and conference paid directly to conference.

Personal non‑specific financial

Advised that as the evidence of the NICE guideline will have been presented he will need to ensure that information he has learnt as being on the GDG is not shared. He agreed and understood.

Lecture on Clostridium difficile multicentre local service evaluation of fidaxomycin.
European Advisory Board on pipeline antibiotics (January 2014) funded by Sanofi.
Lecturing/consultancy about:
– role of the pharmacist in antimicrobial stewardship
– antimicrobial medicine specific topics
– data warehousing
– pipeline agents.
Carried out in September/October 2014. Fees paid into Leeds Teaching Hospitals NHS Trust Charitable Trustees. Funding from Astellas, Baxter, Pfizer and Cubist.

Non‑personal non‑specific financial

Paid by College of Pharmacy Practice and Education to develop Antimicrobials in Focus (Antimicrobial Stewardship for Community Pharmacists).

Personal non‑specific financial

Research funding from Novartis and Astellas paid directly to an independent audit company to undertake audit. Audits not directly related to antimicrobial stewardship topic.

Non‑personal non‑specific financial

Committee member of European Society of Clinical Microbiology and Infectious Diseases, Antimicrobial Stewardship Group (ESGAP). Member of the Department of Health/Public Health England ESPAUR group.

Personal non‑specific non‑financial

Department of Health ARHAI (Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection) Start Smart then Focus guidance for hospitals group.

Personal non‑specific non‑financial

PHE (Public Health England) and RCGP (Royal College of General Practitioners) TARGET AMS for primary care group. PHE (Public Health England)/Department of Health Competencies of Antimicrobial Prescribing and Antimicrobial Stewardship.

Personal non‑specific non‑financial

Lead a research project on surveying antimicrobial stewardship in hospitals across the world.

Personal non‑specific non‑financial

Part of a research group developing an antimicrobial guideline application with a European group "Panacea".

Personal non‑specific non‑financial

Part of a joint NIHR (National Institute for Health Research) Programme grant AMR themed call on behalf of Leeds and Oxford Universities on antimicrobial allergy.

Personal non‑specific non‑financial

Antimicrobial resistance round table group (unfunded) with AstraZeneca to help pharmaceutical industry discussion with Government.

Personal non‑specific non‑financial

Lecture at Clinical Pharmacy Congress (2013 and 2014). Updates provided on respiratory infections in 2013. Updates provided on C. difficile, ESBL and drug allergy in 2014. Payment received directly.

Personal non‑specific financial

Philip Howard

Speaker for Royal Pharmaceutical Society at the Royal Colleges Summit on Antimicrobial Resistance. No payment received.

Non‑specific non‑personal financial

Project lead reiterated the importance that work from this group is not shared with other work that he is involved with. Chair and Project lead will monitor for any potential conflict.

Introduction of proposed ESPAUR/NHS‑England on Quality Premium to reduce antibiotic prescribing.

Specific personal non‑financial

Secondment to NHS England as Regional Healthcare Associated Infections Project Lead from November 2014 to March 2015.

Non‑specific non‑personal financial

Speaker at British Society for Antimicrobial Chemotherapy Antimicrobial Stewardship conference in India.

Non‑specific personal non‑financial

British Society of Antimicrobial Chemotherapy (BSAC) workshop on antimicrobial stewardship in India (27–28 November 2014).

Non‑specific personal non‑financial

Philip Howard

BSAC workshop on antimicrobial stewardship in Bahrain (24–26 February 2015).

Non‑specific, personal non‑financial

Project lead reiterated the importance that work from this group is not shared with other work involved with. Chair and Project lead will monitor for any potential conflict.

BSAC round table talk on pharmacy's role in antimicrobial stewardship.

Personal non‑specific non‑financial

Advisory board for new pipeline product, Durata (February 2015). Fees paid into Leeds Teaching Hospitals NHS Trust Charitable Trustees.

Personal non‑specific financial

Philip Howard

Advisory boards for:
Durata (Dalbavancin) (February 2015)
– Cubist (Tedezolid) (March 2015).
Payment to be made to employer (Leeds Teaching Hospitals) for time.

Personal non‑specific financial

Advised that the GDG discussions remain confidential although the draft guideline contents can be used now they are in the public domain.

Attendance at European Association of Hospital Pharmacy conference. B. Braun paid for accommodation, travel paid and attendance. No direct payment received.

Personal non‑specific non‑financial

Secondment to NHS England as Regional Healthcare Associated Infections Project Lead from November 2014 to March 2015. Extended to June 2015. NHS England payment to Leeds Teaching Hospital Trust for time.

Personal non‑specific non‑financial

Speaker at 3 antimicrobial resistance study days for NHS commissioners and a single C. difficile day (March 2015) (NHS England role).

Personal non‑specific non‑financial

GP C. difficile event in Hull (NHS England role).

Personal non‑specific non‑financial

Part of a Public Health England project on tailoring antimicrobial programmes.

Personal non‑specific non‑financial

Speaker at British Society of Antimicrobial Chemotherapy Gulf Antimicrobial Stewardship conference in Bahrain.

Personal non‑specific non‑financial

National Sepsis Programme Board (March 2015 onwards).

Personal non‑specific non‑financial

POC CRP testing in Primary Care (Alere) – February 15.

Personal non‑specific non‑financial

Philip Howard

Associate for the NICE Medicines and Prescribing Centre.

Non‑specific personal non‑financial

Advised that the GDG discussions remain confidential although the draft guideline contents can be used now they are in the public domain.

Kym Lowder

Stated no conflicts to declare. Spoken at antimicrobial resistance symposia sponsored by public bodies and one by bioMeriuex but received no payment. Leads the development of national Public Health England antibiotic and laboratory use guidance for GPs which covers the diagnosis and treatment of urinary tract infections. She has received grants from several publically funded research bodies.

Personal non‑specific non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc.

Cliodna McNulty

Lead for e‑Bug project across Europe.

Personal non‑specific non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc.

Cliodna McNulty

Member of Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection.

Personal non‑specific non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc.

Cliodna McNulty

Observer on British Society for Antimicrobial Chemotherapy Council.

Personal non‑specific non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc.

Member of English surveillance programme for antimicrobial utilisation and resistance.

Lead in the development of Treat Antibiotics Responsibly, Guidance, Education, Tools (TARGET) and promotes the TARGET resources hosted by the Royal College of General Practitioners.

Cliodna McNulty

Involved in judging the Longitude prize.

Personal non‑specific non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups etc

Cliodna McNulty

Attended advisory board meeting organised by Hayward Medical Communications on 16/05/14 to discuss procalcitonin: event organised on behalf of Thermo Fischer. Honorarium paid to University Hospital Southampton, travel expenses reimbursed.

Personal non‑specific non‑financial

None

Sanjay Patel

Has written a paper on antimicrobial stewardship.

Non‑specific personal non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups, etc

Sanjay Patel

Author of book chapter about antimicrobial stewardship in paediatric care. Manuscript prepared April 2015 for Oxford University Press.

Non‑specific personal non‑financial

None

Sanjay Patel

Has had a relevant journal article published.

Personal non‑specific non‑financial

None

Wendy Thompson

Lectured to foundation dentists on antimicrobial prescribing in general dental practice. Guidance to Foundation Dentists in Health Education (North East).

Specific personal non‑financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles

Lecturer on antimicrobial stewardship prescribing at a Local Professional Network event in Chester in in November and sponsored by Colgate.

Wendy Thompson

Offer received from Leeds University re PhD sponsored financially by Leeds University entitled educating patients about dental treatment rather than antibiotic prescriptions for dental pain.

Personal non‑specific financial

Advice given regarding ensuring that information learnt as part of the NICE guideline process is not shared with other committees/groups or included within any written articles.

Lecturing at British Dental Association Conference on prescribing standards and guidance – May 2016 – no financial gain.

Personal non‑specific non‑financial

Wendy Thompson

Represents and works for organisations that support people with faulty immune systems. Antimicrobials are life‑saving medicines for these patients.

Personal non‑specific non‑financial

None

Susan Walsh

Primary Immunodeficiency UK (PID UK) received 2 grants from CSL Behring in the last 12 months. They were unrestricted and were unrelated to antimicrobials.

Non‑personal non‑specific financial

None

Susan Walsh

Restricted grant from Biotest UK Ltd to PID UK.

Non‑personal non‑specific financial

None

Sponsorship from Bio Products Laboratory Ltd to attend a European Society for Immunodeficiencies conference – unrelated to antimicrobial stewardship.

Susan Walsh

Appointment as community member of NICE Public Health Advisory Committee: guideline on 'Antimicrobial resistance: changing risk‑related behaviours in the general population' (confirmed 27 January 2015).

Non‑personal non‑specific financial

None

  • National Institute for Health and Care Excellence (NICE)