Recommendations for research

The guideline committee has made the following recommendations for research.

Key recommendations for research

1 Availability of PrEP

What is the effectiveness and cost effectiveness of providing pre-exposure prophylaxis (PrEP) outside sexual health services, and does this reach eligible population groups different from those who do access sexual health services?

For a short explanation of why the committee made this recommendation for research, see the rationale section on access to PrEP services.

Full details of the evidence and the committee's discussion are in evidence review G: effectiveness, cost effectiveness, acceptability and unintended consequences of PrEP for HIV.

2 Mode of PrEP delivery

What are the effectiveness, cost effectiveness, availability (eligibility status), adherence considerations, and short- and long-term adverse effects (including impact on bone density) of different modes of delivery, particularly long-acting PrEP (such as injections), including in women?

For a short explanation of why the committee made this recommendation for research, see the rationale section on prescribing PrEP.

Full details of the evidence and the committee's discussion are in evidence review G: effectiveness, cost effectiveness, acceptability and unintended consequences of PrEP for HIV.

3 Delivering effective sexual health services as part of other services

How can sexual health services best be delivered together with other services (for example, drug and alcohol services)?

4 Tailoring outreach services

How can outreach be tailored to specific groups to increase their access to sexual health services and their uptake of STI testing?

5 Reducing stigma

What are the most effective and cost-effective methods of reducing the stigma associated with accessing sexual health services?

Other recommendations for research

Value of incentives

What incentives are effective and cost effective in increasing STI testing and diagnosis, and what, if any, are the adverse and unintended consequences?

Vaccination course completion

What factors affect whether people complete the full course of hepatitis A and B or human papillomavirus (HPV) vaccinations and how do people think they might be encouraged to complete it?

Eligibility for PrEP

What is the cost effectiveness of providing PrEP to people who do not report recent condomless sex?

For a short explanation of why the committee made this recommendation for research, see the rationale section on raising awareness of pre-exposure prophylaxis for HIV.

Full details of the evidence and the committee's discussion are in evidence review G: effectiveness, cost effectiveness, acceptability and unintended consequences of PrEP for HIV.

Remote self-sampling

Have people's attitudes to remote self-sampling and regular testing for STIs changed as a result of self-sampling for COVID‑19?

What are the effectiveness and adverse outcomes of self-sampling for people with symptoms, if remote triage (for example, phone triage) indicates that this is appropriate?

Delivering effective sexual health services

What are the experiences of LGBT+ people in accessing STI testing services, including online?

  • National Institute for Health and Care Excellence (NICE)