This guideline covers preventing, identifying and managing latent and active tuberculosis (TB) in children, young people and adults. It aims to improve ways of finding people who have TB in the community and recommends that everyone under 65 with latent TB should be treated. It describes how TB services should be organised, including the role of the TB control board.

In May 2016, recommendation was clarified to reflect the sequencing of tests. Reference to IGRA status was removed from recommendations;;; and


The guideline includes recommendations on:

Who is it for?

  • Healthcare professionals and TB multidisciplinary teams
  • Substance misuse services, prisons and immigration removal centres
  • Local government and commissioners
  • TB control boards, directors of public health and public health consultants
  • Public Health England and NHS England
  • Voluntary sector workers
  • People with TB and their carers

Guideline development process

How we develop NICE guidelines

This guideline updates and replaces tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control (CG117) and incorporates NICE’s guideline on identifying and managing tuberculosis among hard-to-reach groups (PH37).

Your responsibility

The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The application of the recommendations in this guideline is not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian.

Local commissioners and/or providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties.

Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible.

  • National Institute for Health and Care Excellence (NICE)