Fenfluramine for treating seizures associated with Lennox–Gastaut syndrome in people 2 years and over (TA1050)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 26 March 2025
Ganaxolone for treating seizures caused by CDKL5 deficiency disorder in people 2 years and over (TA1033)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 12 February 2025
Anhydrous sodium thiosulfate for preventing hearing loss caused by cisplatin chemotherapy in people 1 month to 17 years with localised solid tumours (TA1034)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 22 January 2025
Vamorolone for treating Duchenne muscular dystrophy in people 4 years and over (TA1031)Product type:GuidanceProgramme:Technology appraisal guidancePublished: 16 January 2025
Maternal and child nutrition: nutrition and weight management in pregnancy, and nutrition in children up to 5 years (NG247)Product type:GuidanceProgramme:NICE guidelinePublished: 15 January 2025
Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN) (NG245)Product type:GuidanceProgramme:NICE guidelinePublished: 27 November 2024
Digital therapy for chronic tic disorders and Tourette syndrome: early value assessmentStatus:In developmentProgramme:Health technology evaluationExpected publication date: 7 May 2025
Somapacitan for treating growth hormone deficiency in people 3 to 17 years [ID6178]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 29 May 2025
Eflornithine for treating high-risk neuroblastoma with complete or partial response after immunotherapy [ID4060]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 25 June 2025
Vanzacaftor–tezacaftor–deutivacaftor for treating cystic fibrosis with 1 or more F508del mutations in the CFTR gene in people aged 6 years and over [ID6372]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 21 August 2025
Digital self-help for people with eating disorders: early value assessmentStatus:In developmentProgramme:Health technology evaluationExpected publication date: 13 November 2025
Perampanel for adjunctive treatment of partial onset or generalised tonic-clonic seizures in children aged below 12 years with epilepsy [ID1587]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Vosoritide for treating achondroplasia in children and young people under 18 years [ID3807]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Dupilumab for maintenance treatment of uncontrolled moderate to severe asthma in children 6 to 11 years [TSID10085]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Baricitinib for treating moderate to severe atopic dermatitis in children and young people aged 2 to 17 [TSID10639]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Darunavir plus cobicistat fixed dose combination for paediatric human immunodeficiency virus 1 infection [TSID10722]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Dupilumab for children with severe atopic dermatitis [TSID10434]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Dulaglutide for treating type 2 diabetes in children and young people [TSID10660]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Mirabegron for treating neurogenic detrusor overactivity in people aged 3 to 17 [TSID10730]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Dimethyl fumarate for treating relapsing-remitting multiple sclerosis in people aged 13 to 17 [TSID11778]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Crizotinib for treating ALK-positive anaplastic large cell lymphoma or inflammatory myofibroblastic tumour in people 6 to 17 years [TSID10574]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Crizanlizumab for preventing recurrent vaso-occlusive crises in sickle cell disease in young people aged 12 to 17 [TSID10766]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Macitentan for treating pulmonary arterial hypertension in people 1 month to 17 years [TSID11805]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Evinacumab for treating homozygous familial hypercholesterolemia in children aged 6 months to 11 [TSID11806]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Subcutaneous belimumab for treating systemic lupus erythematosus in children aged 5 to 17 [TSID11828]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Ceftobiprole medocaril for treating community- or hospital-acquired pneumonia in people 3 months to 17 years [TSID11819]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Setmelanotide for treating obesity caused by a rare genetic disorder in children aged 2 to 5 [TSID11827]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Sarilumab for treating polyarticular or oligoarticular juvenile idiopathic arthritis in people 2 to 17 years [TSID10237]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Letermovir for preventing cytomegalovirus infection in people under 18 years after allogeneic haematopoietic stem cell transplant [TS ID 11868]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Canagliflozin for treating type 2 diabetes in people 10 to 17 years [TSID11888]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Cerliponase alfa for treating neuronal ceroid lipofuscinosis type 2 (MA review of HST12) [ID6145]Status:In developmentProgramme:Highly specialised technologies guidanceExpected publication date: TBC
Leriglitazone for treating X-linked andrenoleukodystrophy [TSID9996]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Pitolisant for treating narcolepsy in children and young people 6 to 17 years ID6353Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Cipaglucosidase alfa with miglustat for treating late-onset Pompe disease in people 12 to 17 years [TSID11887]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Setmelanotide for treating acquired hypothalamic obesity in people 4 years and older [ID6542]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Odevixibat for treating biliary atresia in children following Kasai hepatoportoenterostomy [TSID11996]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Vosoritide for treating achondroplasia in people 4 months and over ID6488Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Guselkumab for treating chronic plaque psoriasis in children aged 6 to 17 years [TSID12002]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Ustekinumab for the treatment of moderately to severely active Crohn's disease in children [TS ID 11955]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
12 SQ-HDM SLIT for treating allergic rhinitis or rhinoconjunctivitis caused by house dust mites in children 5 to 11 years [ID6510]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Selumetinib granules for treating symptomatic and inoperable plexiform neurofibromas associated with type 1 neurofibromatosis in children 1 to 6 years [TSID12092]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Entrectinib for treating NTRK fusion-positive solid tumours in people 1 month to 11 years [TSID12116]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Soticlestat for treating seizures associated with Dravet syndrome in people 2 years and over TSID 12091Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Ustekinumab for treating moderately to severely active ulcerative colitis in children aged 2 to 17 years [TSID 12128]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Berotralstat for preventing recurrent attacks of hereditary angioedema in children aged 2 to 12 years [TSID 12132]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Lebrikizumab for treating atopic dermatitis in children [TSID 12133_TSID 12135]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Baricitinib for treating severe or very severe alopecia areata in people 6 to 17 years [TSID12142]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Clascoterone for treating acne vulgaris in people 12 years and over [TSID12136]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Inclisiran for treating familial hypercholesterolaemia and elevated low density lipoprotein cholesterol in people 12 to 17 years [TSID12129]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Navepegritide for treating achondroplasia in people 2 to 15 years [ID6538]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Tirzepatide for treating type 2 diabetes in people 10 to 17 years [TSID12131]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Sulthiame for treating self-limiting epilepsy with centrotemporal spikes in children TSID 12106Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Vedolizumab for treating moderately to severely active ulcerative colitis in people 2 to 17 years [TSID12134]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Linaclotide acetate for treating functional constipation in people 6 to 17 years [TSID12125]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Paediatric lymphatic interventions (mainly Percutaneous thoracic duct embolisation) for Chylothorax, chylous ascites, plastic bronchitis, chylopericardium, Chyluria, Protein losing enteropathyStatus:Topic selectionProgramme:Interventional procedures guidanceExpected publication date: TBC
NEMOST growing domino for Neuromuscular early onset scoliosis with Risser 0 in first surgical intentionStatus:Topic selectionProgramme:Interventional procedures guidanceExpected publication date: TBC
Baloxavir marboxil for treating and preventing influenza in children 1 to 11 years [ID6554]Status:Topic selectionProgramme:Technology appraisal guidanceExpected publication date: TBC
Ritlecitinib for treating non-segmental vitiligo in people 12 years and over [TSID12187]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Axatilimab for treating active chronic graft-versus-host disease after 2 or more systemic treatments in people 2 years and over [TSID12189]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Onasemnogene abeparvovec for treating spinal muscular atrophy in people 2 years and over [TSID12168]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Rocatinlimab for treating moderate to severe atopic dermatitis in people 12 years and over [ID6565]Status:Awaiting developmentProgramme:Technology appraisal guidanceExpected publication date: TBC