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Published guidance, NICE advice and quality standards
Title
Reference number
Published
Last updated
Artificial intelligence (AI) technologies to help detect or characterise colorectal polyps
HTG773
19 March 2026
19 March 2026
Pegzilarginase for treating arginase-1 deficiency in people 2 years and over
HST35
4 March 2026
4 March 2026
Cerliponase alfa for treating neuronal ceroid lipofuscinosis type 2
HST34
18 February 2026
18 February 2026
Pulmonary artery pressure technologies for remote monitoring of chronic heart failure
HTG769
5 February 2026
5 February 2026
Leniolisib for treating activated phosphoinositide 3-kinase delta syndrome in people 12 years and over
HST33
23 April 2025
23 April 2025
Burosumab for treating X-linked hypophosphataemia in children and young people
HST8
10 October 2018
8 April 2025
Olipudase alfa for treating acid sphingomyelinase deficiency (Niemann–Pick disease) type AB and type B
HST32
2 April 2025
2 April 2025
Home-testing devices for diagnosing obstructive sleep apnoea hypopnoea syndrome
HTG735
19 December 2024
19 December 2024
Heart failure algorithms for remote monitoring in people with cardiac implantable electronic devices
HTG730
24 October 2024
24 October 2024
Digital technologies for assessing attention deficit hyperactivity disorder (ADHD)
HTG729
21 October 2024
21 October 2024
CYP2C19 genotype testing to guide clopidogrel use after ischaemic stroke or transient ischaemic attack
HTG724
31 July 2024
31 July 2024
Setmelanotide for treating obesity and hyperphagia in Bardet-Biedl syndrome
HST31
22 May 2024
22 May 2024
Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer
HTG719
9 May 2024
9 May 2024
Artificial intelligence (AI)-derived software to help clinical decision making in stroke
HTG708
23 January 2024
2 May 2024
Kurin Lock for blood culture collection
HTG715
3 April 2024
3 April 2024
GaitSmart rehabilitation exercise programme for gait and mobility issues
HTG716
3 April 2024
3 April 2024
Devices for remote monitoring of Parkinson's disease
HTG657
25 January 2023
25 January 2024
Sebelipase alfa for treating Wolman disease
HST30
10 January 2024
10 January 2024
Velmanase alfa for treating alpha-mannosidosis
HST29
13 December 2023
13 December 2023
Birch bark extract for treating epidermolysis bullosa
HST28
20 September 2023
20 September 2023
Quantitative faecal immunochemical testing to guide colorectal cancer pathway referral in primary care
HTG690
24 August 2023
24 August 2023
Afamelanotide for treating erythropoietic protoporphyria
HST27
26 July 2023
26 July 2023
KardiaMobile for detecting atrial fibrillation
HTG606
6 January 2022
25 July 2023
Artificial intelligence (AI)-derived computer-aided detection (CAD) software for detecting and measuring lung nodules in CT scan images
HTG687
5 July 2023
5 July 2023
FibroScan for assessing liver fibrosis and cirrhosis outside secondary and specialist care
HTG682
7 June 2023
7 June 2023
Transperineal biopsy for diagnosing prostate cancer
HTG680
1 June 2023
1 June 2023
MRI fusion biopsy systems for diagnosing prostate cancer
HTG678
24 May 2023
24 May 2023
Automated ankle brachial pressure index measurement devices to detect peripheral arterial disease in people with leg ulcers
HTG677
24 May 2023
24 May 2023
Eladocagene exuparvovec for treating aromatic L-amino acid decarboxylase deficiency
HST26
19 April 2023
19 April 2023
Onasemnogene abeparvovec for treating spinal muscular atrophy
HST15
7 July 2021
19 April 2023
Onasemnogene abeparvovec for treating presymptomatic spinal muscular atrophy
HST24
19 April 2023
19 April 2023
Lumasiran for treating primary hyperoxaluria type 1
HST25
19 April 2023
19 April 2023
AposHealth for knee osteoarthritis
HTG671
11 April 2023
11 April 2023
UrgoStart for treating diabetic foot ulcers and leg ulcers
HTG502
31 January 2019
4 April 2023
Asfotase alfa for treating paediatric-onset hypophosphatasia
HST23
1 March 2023
1 March 2023
Ataluren for treating Duchenne muscular dystrophy with a nonsense mutation in the dystrophin gene
HST22
22 February 2023
22 February 2023
MRI-based technologies for assessing non-alcoholic fatty liver disease
HTG655
12 January 2023
12 January 2023
Memokath 051 Ureter stent for ureteric obstruction
HTG651
7 December 2022
7 December 2022
Optilume for treating recurrent bulbar urethral strictures
HTG649
29 November 2022
29 November 2022
GreenLight XPS for treating benign prostatic hyperplasia
HTG650
29 November 2022
29 November 2022
Magtrace and Sentimag system for locating sentinel lymph nodes for breast cancer
HTG642
5 October 2022
5 October 2022
Neuropad for detecting preclinical diabetic peripheral neuropathy
HTG486
10 September 2018
21 September 2022
Faecal microbiota transplant for recurrent Clostridioides difficile infection
HTG638
31 August 2022
31 August 2022
iFuse for treating chronic sacroiliac joint pain
HTG488
2 October 2018
30 August 2022
SecurAcath for securing percutaneous catheters
HTG440
5 June 2017
10 August 2022
PLGF-based testing to help diagnose suspected preterm pre-eclampsia
HTG630
27 July 2022
27 July 2022
PeritX peritoneal catheter drainage system for vacuum-assisted drainage of treatment-resistant, recurrent malignant ascites
HTG282
21 March 2012
19 July 2022
Setmelanotide for treating obesity caused by LEPR or POMC deficiency
HST21
6 July 2022
6 July 2022
MiraQ for assessing graft flow during coronary artery bypass graft surgery
HTG275
16 November 2011
5 July 2022
Peristeen Plus transanal irrigation system for managing bowel dysfunction
HTG462
23 February 2018
6 June 2022
Thopaz+ portable digital system for managing chest drains
HTG465
21 March 2018
6 June 2022
Sleepio to treat insomnia and insomnia symptoms
HTG624
20 May 2022
20 May 2022
Selumetinib for treating symptomatic and inoperable plexiform neurofibromas associated with type 1 neurofibromatosis in children aged 3 and over
HST20
5 May 2022
5 May 2022
Elosulfase alfa for treating mucopolysaccharidosis type 4A
HST19
20 April 2022
20 April 2022
UroShield for preventing catheter-associated urinary tract infections
HTG620
31 March 2022
31 March 2022
Freelite assays for diagnosing multiple myeloma and related conditions (terminated assessment)
HTG619
30 March 2022
30 March 2022
Atidarsagene autotemcel for treating metachromatic leukodystrophy
HST18
28 March 2022
28 March 2022
Prontosan for treating acute and chronic wounds
HTG616
8 March 2022
8 March 2022
3C Patch for treating diabetic foot ulcers
HTG615
7 March 2022
7 March 2022
PredictSURE IBD and IBDX to guide treatment of Crohn's disease
HTG610
23 February 2022
23 February 2022
EarlyCDT Lung for assessing risk of lung cancer in solid lung nodules
HTG611
23 February 2022
23 February 2022
Odevixibat for treating progressive familial intrahepatic cholestasis
HST17
22 February 2022
22 February 2022
Sedaconda ACD-S for sedation with volatile anaesthetics in intensive care
HTG607
27 January 2022
27 January 2022
Endo-SPONGE for treating low rectal anastomotic leak
HTG605
16 December 2021
16 December 2021
ClearGuard HD antimicrobial barrier caps for preventing haemodialysis catheter-related bloodstream infections
HTG602
13 December 2021
13 December 2021
Synergo for non-muscle-invasive bladder cancer
HTG601
30 November 2021
30 November 2021
Givosiran for treating acute hepatic porphyria
HST16
24 November 2021
24 November 2021
SeHCAT (tauroselcholic [75 selenium] acid) for diagnosing bile acid diarrhoea
HTG598
17 November 2021
17 November 2021
DyeVert Systems for reducing the risk of acute kidney injury in coronary and peripheral angiography
HTG594
4 October 2021
4 October 2021
ENDURALIFE powered CRT-D devices for treating heart failure
HTG433
17 March 2017
21 July 2021
Plus Sutures for preventing surgical site infection
HTG586
28 June 2021
28 June 2021
HeartFlow FFRCT for estimating fractional flow reserve from coronary CT angiography
HTG429
13 February 2017
19 May 2021
Parafricta Bootees and Undergarments to reduce skin breakdown in people with or at risk of pressure ulcers
HTG355
12 November 2014
19 May 2021
UroLift for treating lower urinary tract symptoms of benign prostatic hyperplasia
HTG578
4 May 2021
4 May 2021
Danis stent for acute oesophageal variceal bleeding
HTG574
31 March 2021
31 March 2021
QAngio XA 3D QFR and CAAS vFFR imaging software for assessing coronary stenosis during invasive coronary angiography
HTG571
17 March 2021
17 March 2021
Alpha-Stim AID for anxiety disorders
HTG570
8 March 2021
8 March 2021
Metreleptin for treating lipodystrophy
HST14
24 February 2021
24 February 2021
Leukomed Sorbact for preventing surgical site infection
HTG567
3 February 2021
3 February 2021
The VAC Veraflo Therapy system for acute infected or chronic wounds that are failing to heal
HTG566
27 January 2021
27 January 2021
The PLASMA system for transurethral resection and haemostasis of the prostate
HTG563
6 January 2021
6 January 2021
Zio XT for detecting cardiac arrhythmias
HTG562
1 December 2020
1 December 2020
Testing strategies for Lynch syndrome in people with endometrial cancer
HTG557
28 October 2020
28 October 2020
Volanesorsen for treating familial chylomicronaemia syndrome
HST13
21 October 2020
21 October 2020
SEM Scanner 200 for preventing pressure ulcers
HTG556
14 October 2020
14 October 2020
Axonics sacral neuromodulation system for treating refractory overactive bladder
HTG554
3 September 2020
3 September 2020
Implantable cardiac monitors to detect atrial fibrillation after cryptogenic stroke
HTG553
2 September 2020
2 September 2020
High-sensitivity troponin tests for the early rule out of NSTEMI
HTG552
26 August 2020
26 August 2020
Rezum for treating lower urinary tract symptoms secondary to benign prostatic hyperplasia
HTG545
24 June 2020
24 June 2020
Tests to help assess risk of acute kidney injury for people being considered for critical care admission (ARCHITECT and Alinity i Urine NGAL assays, BioPorto NGAL test and NephroCheck test)
HTG544
17 June 2020
17 June 2020
PneuX to prevent ventilator-associated pneumonia
HTG543
8 April 2020
8 April 2020
SepsiTest assay for rapidly identifying bloodstream bacteria and fungi
HTG400
10 February 2016
19 February 2020
Episcissors-60 for mediolateral episiotomy
HTG538
11 February 2020
11 February 2020
Virtual Touch Quantification to diagnose and monitor liver fibrosis in chronic hepatitis B and C
HTG385
23 September 2015
17 January 2020
gammaCore for cluster headache
HTG533
3 December 2019
3 December 2019
Rapid tests for group A streptococcal infections in people with a sore throat
HTG531
13 November 2019
13 November 2019
Point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast
HTG530
13 November 2019
13 November 2019
Voretigene neparvovec for treating inherited retinal dystrophies caused by RPE65 gene mutations
HST11
9 October 2019
9 October 2019
EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing
HTG296
9 January 2013
8 October 2019
Tegaderm CHG securement dressing for vascular access sites in critically ill adults
HTG379
22 July 2015
18 September 2019
Patisiran for treating hereditary transthyretin amyloidosis
HST10
14 August 2019
14 August 2019
PICO negative pressure wound dressings for closed surgical incisions
HTG509
9 May 2019
6 August 2019
Therapeutic monitoring of TNF-alpha inhibitors in rheumatoid arthritis
HTG521
10 July 2019
10 July 2019
Ambu aScope4 Broncho for use in unexpected difficult airways
HTG312
17 July 2013
17 June 2019
Endocuff Vision for assisting visualisation during colonoscopy
HTG514
7 June 2019
7 June 2019
The Sherlock 3CG Tip Confirmation System for placement of peripherally inserted central catheters
HTG368
25 March 2015
30 May 2019
Curos for preventing infections when using needleless connectors
HTG510
9 May 2019
9 May 2019
Lead-I ECG devices for detecting symptomatic atrial fibrillation using single time point testing in primary care
HTG508
8 May 2019
8 May 2019
The Debrisoft monofilament debridement pad for use in acute or chronic wounds
HTG334
25 March 2014
25 March 2019
Senza spinal cord stimulation system for delivering HF10 therapy to treat chronic neuropathic pain
HTG498
23 January 2019
23 January 2019
Mepilex Border Heel and Sacrum dressings for preventing pressure ulcers
HTG495
10 January 2019
10 January 2019
Pipeline Flex embolisation device with Shield Technology for the treatment of complex intracranial aneurysms
HTG287
30 May 2012
9 January 2019
E‑vita open plus for treating complex aneurysms and dissections of the thoracic aorta
HTG326
18 December 2013
1 October 2018
Biomarker tests to help diagnose preterm labour in women with intact membranes
HTG476
4 July 2018
4 July 2018
Adjunctive colposcopy technologies for assessing suspected cervical abnormalities: the DYSIS colposcope with DYSISmap and the ZedScan I
HTG467
25 April 2018
25 April 2018
Strimvelis for treating adenosine deaminase deficiency–severe combined immunodeficiency
HST7
7 February 2018
7 February 2018
Atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers (the CoaguChek XS system)
HTG353
24 September 2014
19 December 2017
Tests in secondary care to identify people at high risk of ovarian cancer
HTG453
15 November 2017
15 November 2017
moorLDI2-BI: a laser doppler blood flow imager for burn wound assessment
HTG257
25 March 2011
7 August 2017
New generation cardiac CT scanners (Aquilion ONE, Brilliance iCT, Discovery CT750 HD and Somatom Definition Flash) for cardiac imaging in people with suspected or known coronary artery disease in whom imaging is difficult with earlier generation CT scanners
HTG281
25 January 2012
6 July 2017
Eliglustat for treating type 1 Gaucher disease
HST5
28 June 2017
28 June 2017
Multiple frequency bioimpedance devices to guide fluid management in people with chronic kidney disease having dialysis
HTG441
21 June 2017
21 June 2017
Virtual chromoendoscopy to assess colorectal polyps during colonoscopy
HTG438
10 May 2017
10 May 2017
Migalastat for treating Fabry disease
HST4
22 February 2017
22 February 2017
Molecular testing strategies for Lynch syndrome in people with colorectal cancer
HTG430
22 February 2017
22 February 2017
HumiGard for preventing inadvertent perioperative hypothermia
HTG428
8 February 2017
8 February 2017
XprESS multi sinus dilation system for treating chronic sinusitis
HTG424
13 December 2016
13 December 2016
High-throughput non-invasive prenatal testing for fetal RHD genotype
HTG420
9 November 2016
9 November 2016
ImmunoCAP ISAC 112 for multiplex allergen testing
HTG413
18 May 2016
18 May 2016
Spectra Optia for automatic red blood cell exchange in people with sickle cell disease
HTG405
2 March 2016
2 March 2016
Therapeutic monitoring of TNF-alpha inhibitors in Crohn's disease (LISA-TRACKER ELISA kits, IDKmonitor ELISA kits, and Promonitor ELISA kits)
HTG401
17 February 2016
17 February 2016
VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesions
HTG388
11 November 2015
11 November 2015
Procalcitonin testing for diagnosing and monitoring sepsis (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay)
HTG386
7 October 2015
7 October 2015
VibraTip for testing vibration perception to detect diabetic peripheral neuropathy
HTG362
31 December 2014
1 March 2015
Eculizumab for treating atypical haemolytic uraemic syndrome
HST1
28 January 2015
28 January 2015
Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment
HTG360
10 December 2014
10 December 2014
The ReCell Spray‑On Skin system for treating skin loss, scarring and depigmentation after burn injury
HTG356
12 November 2014
12 November 2014
Detecting, managing and monitoring haemostasis: viscoelastometric point‑of‑care testing (ROTEM, TEG and Sonoclot systems)
HTG348
20 August 2014
20 August 2014
The geko device for reducing the risk of venous thromboembolism
HTG344
25 June 2014
25 June 2014
Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel
HTG320
2 October 2013
2 October 2013
EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer
HTG316
14 August 2013
14 August 2013
Intraoperative tests (RD‑100i OSNA system and Metasin test) for detecting sentinel lymph node metastases in breast cancer
HTG315
7 August 2013
7 August 2013
Depth of anaesthesia monitors – Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M
HTG292
21 November 2012
21 November 2012
SonoVue (sulphur hexafluoride microbubbles) – contrast agent for contrast-enhanced ultrasound imaging of the liver
HTG291
29 August 2012
29 August 2012
Mega Soft Patient Return Electrode for use during monopolar electrosurgery
HTG290
22 August 2012
22 August 2012
The EOS 2D/3D imaging system
HTG274
26 October 2011
26 October 2011
The MIST Therapy system for the promotion of wound healing
HTG267
25 July 2011
25 July 2011
Ambulight PDT for the treatment of non-melanoma skin cancer
HTG268
25 July 2011
25 July 2011
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