Quality statement 6: Thrombophilia testing

Quality statement

People with provoked deep vein thrombosis or pulmonary embolism are not offered testing for thrombophilia.

Rationale

Thrombophilia testing does not provide benefit and is unnecessary for people with provoked deep vein thrombosis (DVT) or pulmonary embolism (PE).

Quality measures

Structure

Evidence of local arrangements to ensure people with provoked DVT or PE do not have testing for thrombophilia.

Data source: Local data collection.

Process

The proportion of people with provoked DVT or PE who are tested for thrombophilia.

Numerator – the number of people in the denominator who receive testing for thrombophilia.

Denominator – the number of people with provoked DVT or PE.

Data source: Local data collection.

What the quality statement means for different audiences

Service providers ensure systems are in place to ensure that people with provoked DVT or PE are not tested for thrombophilia.

Healthcare professionals ensure people with provoked DVT or PE are not tested for thrombophilia.

Commissioners ensure they commission services that do not carry out testing for thrombophilia in people with provoked DVT or PE.

People who have had a provoked (with an obvious cause) deep vein thrombosis or pulmonary embolism are not offered tests for thrombophilia (a condition that makes the blood more likely to form clots).

Definition

Provoked DVT or PE

DVT or PE in a person with a recent (within 3 months) and transient major clinical risk factor for VTE – such as surgery, trauma, significant immobility (bedbound, unable to walk unaided or likely to spend a substantial proportion of the day in bed or in a chair), pregnancy or puerperium – or in a person who is having hormonal therapy (combined oral contraceptive pill or hormone replacement therapy). [NICE's guideline on venous thromboembolic diseases, terms used in this guideline section]