Appendix B: Sources of evidence considered by the Committee

Appendix B: Sources of evidence considered by the Committee

A. The Evidence Review Group (ERG) report for this appraisal was prepared by the School of Health and Related Research (ScHARR), The University of Sheffield:

  • Stevenson M, Pandor A, Febuxostat for the management of hyperuricaemia in patients with gout, March 2008

B. The following organisations accepted the invitation to participate in this appraisal. They were invited to comment on the draft scope, the ERG report and the appraisal consultation document (ACD). Organisations listed in I were also invited to make written submissions. Organisations listed in II and III had the opportunity to give their expert views. Organisations listed in I, II and III also had the opportunity to appeal against the final appraisal determination.

I) Manufacturer/sponsor:

  • Ipsen

II) Professional/specialist and patient/carer groups:

  • Arthritis Care

  • Kidney Research UK

  • South Asian Health Foundation

  • Royal College of Physicians

  • Royal College of Pathologists

  • Royal College of Nursing

  • Royal College of General Practitioners

  • Primary Care Rheumatology Society

  • British Society for Rheumatology

III) Other consultees:

  • Welsh Assembly Government

IV) Commentator organisations (did not provide written evidence and without the right of appeal):

  • NHS Quality Improvement Scotland

C. The following individuals were selected from clinical specialist and patient advocate nominations from the non-manufacturer/sponsor consultees and commentators. They gave their expert personal view on febuxostat by attending the initial Committee discussion and providing written evidence to the Committee. They were also invited to comment on the ACD.

  • Dr Paramit Chowdhury, Consultant Nephrologist, Guy's and St Thomas' (nominated by the Royal College of Physicians) – clinical specialist

  • Dr Paul Collinson, Consultant Chemical Pathologist, St George's Hospital, London (nominated by the Royal College of Pathologists) – clinical specialist

  • Professor Michael Doherty, Professor of Rheumatology, University of Nottingham (nominated by the British Society for Rheumatology) – clinical specialist

  • Mr Iain Phillips (nominated by the UK Gout Society) – patient expert

  • National Institute for Health and Care Excellence (NICE)