Information

Information

NHS organisations should take into account the reasons why the manufacturer did not make an evidence submission when considering whether or not to recommend local use of methylnaltrexone for treating opioid-induced bowel dysfunction in people with advanced illness receiving palliative care. If, after doing this, organisations still wish to consider methylnaltrexone for treating opioid-induced bowel dysfunction in people with advanced illness receiving palliative care, they should follow the advice set out in Good practice guidance on managing the introduction of new healthcare interventions and links to NICE technology appraisal guidance which outlines the approach that should be adopted in circumstances where NICE guidance is unavailable.

NICE will review the position at any point if the manufacturer indicates that it wishes to make a full submission.

Related NICE guidance

For information about NICE guidance that has been issued or is in development, see the NICE website.

Under development

NICE is developing the following guidance (details available from the NICE website):

  • Lubiprostone for the treatment of opioid-induced constipation. NICE technology appraisal. Publication date to be confirmed.

  • National Institute for Health and Care Excellence (NICE)