Information for the public
What has NICE said?
Lubiprostone is recommended as a possible treatment for people with chronic idiopathic constipation:
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who have previously been treated with 2 different types of laxatives at the highest possible recommended dose, for at least 6 months, but these haven't worked well enough, and
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when invasive treatment is being considered.
If treatment with lubiprostone has not worked after 2 weeks, your doctor will talk to you about whether or not you should keep taking this medicine. Lubiprostone should only be prescribed for you by a doctor who is experienced in treating chronic idiopathic constipation, after they have carefully considered your previous treatments.
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