Table of Contents

01 - Pre-Meeting Briefing prepared by NICE

02 - Submission from the technology company Novartis

03 - NICE request to the company for clarification on their submission

04 - NICE request to the company for additional clarification on their submission

05 - Company clarification response

06 - Consultee submission - Esprit

07 - Consultee submission - Royal College of Pathologist

08 - Clinical expert personal perspective - Newsome

09 - Clinical expert personal perspective - Manas

10 - Patient expert personal perspective -Hall

11 - Patient expert personal perspective - Langford

12 - Evidence Review Group report prepared by PenTAG

13 - Company factual accuracy check of Evidence Review Group report

14 - ERG critique Response - Erratum prepared by PenTAG