History A list of downloadable documents created during development. Final appraisal determination Final appraisal determination Final appraisal determination document PDF 734 KB 05 October 2017 Committee papers PDF 2.94 MB 05 October 2017 Public committee slides PowerPoint 512 KB 05 October 2017 Final appraisal determination document CDF Glossary of terms PDF 123 KB 05 October 2017 Final appraisal determination document Managed Access Agreement PDF 503 KB 17 April 2018 Appraisal consultation: 2 Appraisal consultation: 2 Appraisal consultation document PDF 580 KB 11 May 2017 Committee papers PDF 2.32 MB 11 May 2017 Public committee slides PDF 621 KB 11 May 2017 Appraisal consultation: 1 Appraisal consultation: 1 Appraisal consultation document PDF 473 KB 15 February 2017 Committee papers PDF 9.56 MB 15 February 2017 Public committee slides PDF 698 KB 15 February 2017 Invitation to participate Final scope PDF 135 KB 15 August 2016 Final matrix PDF 96 KB 15 August 2016 NICE's response to comments on the draft scope and provisional matrix PDF 292 KB 15 August 2016 Equality Impact Assessment (Guidance development) PDF 120 KB 15 August 2016 Final scope November 2016 PDF 245 KB 14 November 2016 Final matrix November 2016 PDF 256 KB 14 November 2016 Final scope December 2016 PDF 250 KB 21 December 2016 Draft scope documents Draft scope (post-referral) PDF 140 KB 22 July 2016 Provisional matrix (post-referral) PDF 97 KB 22 July 2016 Draft scope documents Draft scope (pre-referral) PDF 111 KB 08 July 2016 Provisional matrix (pre-referral) PDF 99 KB 08 July 2016