Guidance
2 Information about ixazomib
2 Information about ixazomib
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Marketing authorisation indication |
Ixazomib citrate (Ninlaro, Takeda), in combination with lenalidomide and dexamethasone, has a marketing authorisation for 'the treatment of adult patients with multiple myeloma who have had at least 1 previous therapy'. |
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Dosage in the marketing authorisation |
Oral capsules, 4 mg once a week on days 1, 8, and 15 of a 28-day cycle. Taken with lenalidomide 25 mg daily on days 1 to 21 of the cycle and dexamethasone 40 mg on days 1, 8, 15, and 22 of the cycle. |
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Price |
£6,336 per cycle (3 capsules, excluding VAT; NHS Dictionary of Medicines and Devices [accessed November 2017]). As part of the managed access agreement, the company has a commercial access agreement with NHS England. This makes ixazomib available at a reduced cost. The financial terms of the agreement are commercial in confidence. |