Changes after publication
January 2014: implementation section updated to clarify that electroconvulsive therapy is recommended as an option for treating catatonia or a prolonged or severe manic episode. Additional minor maintenance update also carried out.
March 2012: minor maintenance
The recommendations in this technology appraisal relating to the treatment of depression have been replaced by recommendations in 'Depression in adults (update)' (NICE clinical guideline 90) published in October 2009). Note that the recommendations in this technology appraisal relating to the treatment of catatonia-prolonged or severe manic episodes and schizophrenia have not changed. The recommendations relating to depression have been removed from this web viewer version.