Information for the public

Selpercatinib (Retsevmo) is available through the Cancer Drugs Fund as a possible treatment for:

  • advanced RET fusion-positive thyroid cancer in adults who need systemic therapy after sorafenib or lenvatinib
  • advanced RET-mutant medullary thyroid cancer in people 12 years and older who need systemic therapy after cabozantinib or vandentanib.

More evidence on selpercatinib is being collected, until November 2024. After this NICE will decide whether or not to recommend selpercatinib for use on the NHS and update the guidance. It will be available through the Cancer Drugs Fund until then.

If you are not eligible for selpercatinib but are already having it, you should be able to continue until you and your doctor decide when best to stop.

Is this treatment right for me?

Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. Read more about making decisions about your care.

Questions to think about

  • How well does it work compared with other treatments?
  • What are the risks or side effects? How likely are they?
  • How will the treatment affect my day-to-day life?
  • What happens if the treatment does not work?
  • What happens if I do not want to have treatment? Are there other treatments available?

Information and support

The NHS website may be a good place to find out more.

These organisations can give you advice and support:

You can also get support from your local Healthwatch.

NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.

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